ArticleCortex; a journal devoted to the study of the nervous system and behavior2019
A structural connectivity convergence zone in the ventral and anterior temporal lobes: Data-driven evidence from structural imaging.
Article in Cortex; a journal devoted to the study of the nervous system and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 36 citations in OpenAlex.
- Bridging Continuous and Discrete Models of the Anterior Temporal Lobe via Cortical Gradients.Research square · 2026Article
- Mapping Contributions of the Anterior Temporal Semantic Hub to the Processing of Abstract and Concrete Verbs.Human brain mapping · 2025Article
- Clinical Manifestations and Neural Basis of Semantic Dementia: Converging Evidences From Brain Imaging Studies.Clinical interventions in aging · 2025Review
- The neurobiology of interoception and affect.Trends in cognitive sciences · 2024Review
- Graded functional organization in the left inferior frontal gyrus: evidence from task-free and task-based functional connectivity.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- A middle ground where executive control meets semantics: the neural substrates of semantic control are topographically sandwiched between the multiple-demand and default-mode systems.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- The role of the ventrolateral anterior temporal lobes in social cognition.Human brain mapping · 2022Article
- The organization of individually mapped structural and functional semantic networks in aging adults.Brain structure & function · 2022Article
- A tale of two gradients: differences between the left and right hemispheres predict semantic cognition.Brain structure & function · 2022Article
- Frontotemporal dementia: A unique window on the functional role of the temporal lobes.Handbook of clinical neurology · 2022Review
- Structural Connectivity Gradients of the Temporal Lobe Serve as Multiscale Axes of Brain Organization and Cortical Evolution.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Implicit, automatic semantic word categorisation in the left occipito-temporal cortex as revealed by fast periodic visual stimulation.NeuroImage · 2021Article
- Article
- Bipartite Functional Fractionation within the Default Network Supports Disparate Forms of Internally Oriented Cognition.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Dynamic activity patterns in the anterior temporal lobe represents object semantics.Cognitive neuroscience · 2020Article
- Principles of temporal association cortex organisation as revealed by connectivity gradients.Brain structure & function · 2020Article
- Regional and hemispheric susceptibility of the temporal lobe to FTLD-TDP type C pathology.NeuroImage. Clinical · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
The hub-and-spoke model of semantic cognition seeks to reconcile embodied views of a fully distributed semantic network with patient evidence, primarily from semantic dementia, who demonstrate modality-independent conceptual deficits associated with atrophy centred on the ventrolateral anterior temporal lobe. The proponents of this model have recently suggested that the temporal cortex is a graded representational space where concepts become less linked to a specific modality as they are processed farther away from primary and secondary sensory cortices and towards the ventral anterior temporal lobe. To explore whether there is evidence that the connectivity patterns of the temporal lobe converge in its ventral anterior end the current study uses three dimensional Laplacian eigenmapping, a technique that allows visualisation of similarity in a low dimensional space. In this space similarity is encoded in terms of distances between data points. We found that the ventral and anterior temporal lobe is in a unique position of being at the centre of mass of the data points within the connective similarity space. This can be interpreted as the area where the connectivity profiles of all other temporal cortex voxels converge. This study is the first to explicitly investigate the pattern of connectivity and thus provides the missing link in the evidence that the ventral anterior temporal lobe can be considered a multi-modal graded hub.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.