ReviewBehavioural brain research2019
Contributions of adult neurogenesis to dentate gyrus network activity and computations.
Review in Behavioural brain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
43 citing papers in PubMed, 97 citations in OpenAlex.
- Δ9-Tetrahydrocannabinol Modulates Hippocampal Neurogenesis in Female Wistar Rats: Interaction with Estradiol.Neurochemical research · 2026Article
- Subregional activity in the dentate gyrus is amplified during elevated cognitive demands.eLife · 2026Article
- Postnatal development of the dentate gyrus vascular niche.Scientific reports · 2025Article
- Exercise-Induced Hippocampal Neurogenesis Is Attenuated by Inhibition of Monocarboxylate Transporter 2.Molecular neurobiology · 2025Article
- Open-source, high performance miniature 2-photon microscopy systems for freely behaving animals.Nature communications · 2025Article
- Article
- Analysis of β-Catenin Signalling Activity Suggests Differential Regulation of Ontogenetically Distinct Dentate Granule Neuron Populations.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2025Article
- Autocrine VEGF drives neural stem cell proximity to the adult hippocampus vascular niche.Life science alliance · 2024Article
- Cannabinoid type 2 receptor inhibition enhances the antidepressant and proneurogenic effects of physical exercise after chronic stress.Translational psychiatry · 2024Article
- Robust and consistent measures of pattern separation based on information theory and demonstrated in the dentate gyrus.PLoS computational biology · 2024Article
- Exploring the dynamics of adultFrontiers in neuroscience · 2024Article
- Sharpening the blades of the dentate gyrus: how adult-born neurons differentially modulate diverse aspects of hippocampal learning and memory.The EMBO journal · 2023Review
- Blockade of adenosine AAlzheimer's research & therapy · 2023Article
- Article
- Male Stressed Mice Having Behavioral Control Exhibit Escalations in Dorsal Dentate Adult-Born Neurons and Spatial Memory.International journal of molecular sciences · 2023Article
- Neurotrophic effects of intermittent fasting, calorie restriction and exercise: a review and annotated bibliography.Frontiers in aging · 2023Review
- A Moderate Duration of Stress Promotes Behavioral Adaptation and Spatial Memory in Young C57BL/6J Mice.Brain sciences · 2022Article
- Dominant role of adult neurogenesis-induced structural heterogeneities in driving plasticity heterogeneity in dentate gyrus granule cells.Hippocampus · 2022Article
- Neurogenesis mediated plasticity is associated with reduced neuronal activity in CA1 during context fear memory retrieval.Scientific reports · 2022Article
- Flexible encoding of objects and space in single cells of the dentate gyrus.Current biology : CB · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Anatomical observations, theoretical work and lesion experiments have led to the idea that an important function of the dentate gyrus of the mammalian hippocampus is pattern separation, a neural computation that ensures new memories are encoded without interference from previously stored memories that share similar features. The dentate gyrus also exhibits a unique form of neural plasticity that results from the continuous integration of newly born excitatory granule cells, termed adult hippocampal neurogenesis. However, the manner in which adult neurogenesis contributes to dentate gyrus network activity and computations is incompletely understood. Here, we first describe the prevailing models for the role of adult neurogenesis in dentate gyrus network function and then re-evaluate these models in the light of recent findings regarding the in vivo activity of the dentate gyrus and synaptic interactions of adult born granule cells with local circuit components, as well as, inputs, and outputs of the dentate gyrus. We propose that adult neurogenesis provides flexibility for the dentate gyrus to rapidly generate a context specific, distributed representation of important sensory stimuli such as spatial cues, which ultimately gives rise to behavioral discrimination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.