Evidence map›Paper›PMID 31376979›Full record

ArticleJournal of biomechanics2019

Changes in shear wave propagation within skeletal muscle during active and passive force generation.

Allison B Wang, Eric J Perreault, Thomas J Royston, Sabrina S M Lee

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomechanics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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  14. Hyaluronan homeostasis and its role in pain and muscle stiffness.PM & R : the journal of injury, function, and rehabilitation · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Allison B WangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, USA; Shirley Ryan AbilityLab, Chicago, IL, USA. Electronic address: bwang15@u.northwestern.edu.
Eric J PerreaultDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA; Department of Physical Medicine and Rehabilitation, Northwestern, Chicago, IL, USA; Shirley Ryan AbilityLab, Chicago, IL, USA.
Thomas J RoystonDepartment of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA.
Sabrina S M LeeDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, USA.
Northwestern University · USUniversity of Illinois Chicago · US

Funding

Noninvasive Tools for Assessing Muscle Structure and FunctionR01AR071162 · NIAMS · NORTHWESTERN UNIVERSITY · PI ERIC JON PERREAULT · 2016 to 2026
$6.1M
Interdisciplinary Graduate Education in Movement and Rehabilitation Sciences-RenewalT32EB009406 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JULIUS P DEWALD, JUN YAO · 2009 to 2026
$2.2M
NIAMS NIH HHS R01 AR071162NIBIB NIH HHS T32 EB009406
6 · The paper itself

Abstract

Muscle force can be generated actively through changes in neural excitation, and passively through externally imposed changes in muscle length. Disease and injury can disrupt force generation, but it can be challenging to separate passive from active contributions to these changes. Ultrasound elastography is a promising tool for characterizing the mechanical properties of muscles and the forces that they generate. Most prior work using ultrasound elastography in muscle has focused on the group velocity of shear waves, which increases with increasing muscle force. Few studies have quantified the phase velocity, which depends on the viscoelastic properties of muscle. Since passive and active forces within muscle involve different structures for force transmission, we hypothesized that measures of phase velocity could detect changes in shear wave propagation during active and passive conditions that cannot be detected when considering only group velocity. We measured phase and group velocity in the human biceps brachii during active and passive force generation and quantified the differences in estimates of shear elasticity obtained from each of these measurements. We found that measures of group velocity consistently overestimate the shear elasticity of muscle. We used a Voigt model to characterize the phase velocity and found that the estimated time constant for the Voigt model provided a way to distinguish between passive and active force generation. Our results demonstrate that shear wave elastography can be used to distinguish between passive and active force generation when it is used to characterize the phase velocity of shear waves propagating in muscle.

Indexed as

AdultElasticityElasticity Imaging TechniquesFemaleHumansMaleMuscle, SkeletalReproductionViscosityYoung AdultForcesMuscleShear wave elastographyViscoelastic

Identifiers

PMID31376979
PMCPMC6736689
OpenAlexW2963913288

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.