Evidence map›Paper›PMID 31376500›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2020

Mapping the Research Domain Criteria Social Processes Constructs to the Social Responsiveness Scale.

Mirko Uljarević, Thomas W Frazier, Jennifer M Phillips, Booil Jo, Sandy Littlefield, Antonio Y Hardan

Abstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Parsing the heterogeneity of social motivation in autism.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Article
  8. Psychometric evaluation of the Autism Symptom Dimensions Questionnaire.Developmental medicine and child neurology · 2025
    Article
  9. Review
  10. Article
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  14. Article
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  19. Article
  20. Extracting Latent Subdimensions of Social Communication: A Cross-Measure Factor Analysis.Journal of the American Academy of Child and Adolescent Psychiatry · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Mirko UljarevićStanford University, California. Electronic address: mirkoulj@stanford.edu.
Thomas W FrazierAutism Speaks, New York.
Jennifer M PhillipsStanford University, California.
Booil JoStanford University, California.
Sandy LittlefieldStanford University, California.
Antonio Y HardanStanford University, California.

Funding

Identification of RDoC Social Communication Sub-Constructs Using Existing DatasetsR03MH111846 · NIMH · STANFORD UNIVERSITY · PI HARDAN, ANTONIO · 2017 to 2018
$157k
NIMH NIH HHS R03 MH111846
6 · The paper itself

Abstract

objectiveResearch Domain Criteria (RDoC) operationalizes a set of basic social dimensions that can be used to deconstruct sources of variation in social impairments across affected individuals, regardless of their diagnostic status. This is a necessary step toward the development of etiologically based and individualized treatments. The main objective of this investigation was to derive estimations of the RDoC social constructs from the Social Responsiveness Scale (SRS-2).

methodExploratory structural equation modeling and confirmatory factor analysis were conducted using individual SRS-2 items from six distinct databases ( N = 27,953; mean age = 9.55 years, SD = 3.79; 71.7% male participants) spanning normative (33.8%) and atypical (66.2%) development. The following models were estimated: a one-factor model; a three-factor model with separate attachment and affiliation, social communication, and understanding of mental states factors; and a four-factor model where social communication was further split into production of facial and non-facial communication.

resultsThe one-factor solution showed poor fit. The three-factor solution had adequate fit (comparative fit index = 0.952, Tucker Lewis Index = 0.937, root mean square error of approximation = 0.054). However, the four-factor solution had superior fit (comparative fit index = 0.973, Tucker Lewis Index = 0.961, root mean square error of approximation = 0.042) and was robust across age, sex, and clinical status.

conclusionTo our knowledge, this is the first study examining estimations of the RDoC social constructs from an existing measure. Reported findings show promise for capturing important RDoC social constructs using the SRS-2 and highlight crucial areas for the development of novel dimensional social processing measures.

Indexed as

Factor Analysis, StatisticalChildFemaleHumansMalePsychometricsReproducibility of Resultsheterogeneityneurodevelopmental and neuropsychiatric disordersResearch Domain Criteriasocial processesvariable-centered

Identifiers

PMID31376500
PMCPMC7470629

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.