ArticleBrain, behavior, and immunity2019
Positive mental well-being and immune transcriptional profiles in highly involved videogame players.
Article in Brain, behavior, and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Peer victimization in adolescence alters gene expression and cytokine profiles during transition to adulthood.Brain, behavior, & immunity - health · 2025Article
- Immune transcriptomic profile in adult female pigs: dominance status has more influence than environmental enrichment.BMC genomics · 2024Article
- Neurobiological Link between Stress and Gaming: A Scoping Review.Journal of clinical medicine · 2023Article
- Social connection and gene regulation during the COVID-19 pandemic: Divergent patterns for online and in-person interaction.Psychoneuroendocrinology · 2022Article
- Video Game Addictive Symptom Level, Use Intensity, and Hedonic Experience: Cross-sectional Questionnaire Study.JMIR serious games · 2022Article
- Flourishing in Healthcare Trainees: Psychological Well-Being and the Conserved Transcriptional Response to Adversity.International journal of environmental research and public health · 2022Article
- Video Game Streaming in Young People and Teenagers: Uptake, User Groups, Dangers, and Opportunities.Healthcare (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Previous research has identified a link between experiencing life as meaningful and purposeful-what is referred to as "eudaimonia"-and reduced expression of a stress-induced gene profile known as the "conserved transcriptional response to adversity" (CTRA). In the current study, we examine whether similar links between eudaimonic well-being and CTRA reduction occur in a sample of 56 individuals with a particularly strong engagement with virtual worlds: avid online videogame players. Results consistently linked higher eudaimonic well-being, and more specifically the social well-being subdomain of eudaimonia, to lower levels of CTRA gene expression. That favorable psychobiological relationship between eudaimonia and CTRA appeared most strongly among individuals reporting high levels of positive psychosocial involvement with gaming. Findings are consistent with the hypothesis that committed social/recreational activity may help damp CTRA expression especially among persons who are already experiencing some kind of threshold of positive eudaimonic experience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.