ReviewMolecular and cellular endocrinology2019
Evaluating testosterone as a phenotypic integrator: From tissues to individuals to species.
Review in Molecular and cellular endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Nonapeptide cell size differs between male morphs of the West African cichlid, Pelvicachromis pulcher.Journal of fish biology · 2026Article
- Telomere-Related Gene Networks in the Ovary Shift Across Environmental Factors.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2025Article
- Neurogenomic landscape associated with status-dependent cooperative behaviour.Molecular ecology · 2025Article
- Repeated behavioural evolution is associated with convergence of gene expression in cavity-nesting songbirds.Nature ecology & evolution · 2025Article
- Levels of Sex Steroids in Plethodontid Salamanders: A Comparative Study Within the GenusEcology and evolution · 2024Article
- Climate change and its effects on body size and shape: the role of endocrine mechanisms.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- The evolutionary history and mechanistic basis of female ornamentation in a tropical songbird.Evolution; international journal of organic evolution · 2022Article
- Bidirectional relationships between testosterone and aggression: a critical analysis of four predictions.Integrative and comparative biology · 2022Article
- Testosterone, signal coloration, and signal color perception in male zebra finch contests.Ethology : formerly Zeitschrift fur Tierpsychologie · 2022Article
- Male Bowhead Whale Reproductive Histories Inferred from Baleen Testosterone and Stable Isotopes.Integrative organismal biology (Oxford, England) · 2022Article
- Beyond a biased binary: A perspective on the misconceptions, challenges, and implications of studying females in avian behavioral endocrinology.Frontiers in physiology · 2022Article
- Correlated evolution of distinct signals associated with increased social selection in female white-shouldered fairywrens.Ecology and evolution · 2021Article
- Testosterone regulatesProceedings. Biological sciences · 2020Article
- Article
- Seasonal regulation of behaviour: what role do hormone receptors play?Proceedings. Biological sciences · 2020Article
- How research on female vertebrates contributes to an expanded challenge hypothesis.Hormones and behavior · 2020Review
- Tissue-specific expression profiles and positive selection analysis in the tree swallow (Tachycineta bicolor) using a de novo transcriptome assembly.Scientific reports · 2019Article
- Testing hormonal responses to real and simulated social challenges in a competitive female bird.Behavioral ecology : official journal of the International Society for Behavioral EcologyArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Hormones have the potential to bring about rapid phenotypic change; however, they are highly conserved over millions of years of evolution. Here, we examine the evolution of hormone-mediated phenotypes, and the extent to which regulation is achieved via independence or integration of the many components of endocrine systems. We focus on the sex steroid testosterone (T), its cognate receptor (androgen receptor) and related endocrine components. We pose predictions about the mechanisms underlying phenotypic integration, including coordinated sensitivity to T within and among tissues and along the HPG axis. We then assess these predictions with case studies from wild birds, asking whether gene expression related to androgenic signaling naturally co-varies among individuals in ways that would promote phenotypic integration. Finally, we review how mechanisms of integration and independence vary over developmental or evolutionary time, and we find limited support for integration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.