ArticleGastroenterology2020
Baseline Colonoscopy Findings Associated With 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance.
Article in Gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- NCCN Guidelines Insights: Colorectal Cancer Screening, Version 2.2020.Journal of the National Comprehensive Cancer Network : JNCCN · 2020Guideline
- Adherence to 2020 US Multi-Society Task Force Guidelines for Post-Polypectomy Surveillance: a Multicenter Real-Time Analysis.Journal of gastrointestinal cancer · 2026Article
- Deciding on surveillance colonoscopy: a multi-phase study of a conversation aid for older adults.BMC medical informatics and decision making · 2026Article
- Associations Between Prescreening Dietary Patterns and Longitudinal Colonoscopy Outcomes in Veterans.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025Article
- Surveillance of colorectal neoplasia: a review of guidelines, current evidence, and future directions.Colorectal cancer · 2025Article
- Will Rogers Paradox in Gastroenterology.Digestive diseases and sciences · 2025Review
- Colorectal Cancer Polygenic Risk Score Is Associated With Screening Colonoscopy Findings but Not Follow-Up Outcomes.Gastro hep advances · 2024Article
- Bowel cleansing effectiveness and safety of 1L PEG + Asc in the real-world setting: Observational, retrospective, multicenter study of over 13000 patients.Endoscopy international open · 2023Article
- Colorectal cancer risk after removal of polyps in fecal immunochemical test based screening.EClinicalMedicine · 2023Article
- Clinical outcomes of colonoscopic polypectomy with strategic surveillance colonoscopies in patients with 10 or more polyps.Scientific reports · 2023Observational
- Korean Guidelines for Postpolypectomy Colonoscopic Surveillance: 2022 revised edition.Intestinal research · 2023Review
- Korean guidelines for postpolypectomy colonoscopic surveillance: 2022 revised edition.Clinical endoscopy · 2022Review
- The Present and Future of Colorectal Cancer Screening.Gastroenterology & hepatology · 2022Article
- [Korean Guidelines for Postpolypectomy Colonoscopic Surveillance: 2022 Revised Edition].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2022Review
- Longitudinal assessment of colonoscopy adverse events in the prospective Cooperative Studies Program no. 380 colorectal cancer screening and surveillance cohort.Gastrointestinal endoscopy · 2022Article
- Article
- Ten or More Cumulative Lifetime Adenomas Are Associated with Increased Risk for Advanced Neoplasia and Colorectal Cancer.Digestive diseases and sciences · 2022Article
- Scoping out the future: The application of artificial intelligence to gastrointestinal endoscopy.World journal of gastrointestinal oncology · 2022Review
- Colorectal cancer surveillance by colonoscopy in a prospective, population-based long-term Swiss screening study - outcomes, adherence, and costs.Zeitschrift fur Gastroenterologie · 2022Article
- Prevalence of Metachronous Advanced Colorectal Neoplasia in Black and White Patients at a Safety Net Hospital.Gastro hep advances · 2022Article
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Authors and funding
18 authors at 6 institutions in 1 country.
Funding
Abstract
BACKGROUND &
aimsFew studies have evaluated long-term outcomes of ongoing colonoscopic screening and surveillance in a screening population. We aimed to determine the 10-year risk for advanced neoplasia (defined as adenomas ≥10mm, adenomas with villous histology or high-grade dysplasia, or colorectal cancer [CRC]) and assessed whether baseline colonoscopy findings were associated with long-term outcomes.
methodsWe collected data from the Department of Veterans Affairs Cooperative Studies Program Study on 3121 asymptomatic veterans (50-75 years old) who underwent a screening colonoscopy from 1994 through 1997 at 13 medical centers and were then followed for 10 years or until death. We included 1915 subjects with at least 1 surveillance colonoscopy and estimated cumulative incidence of advanced neoplasia by Kaplan-Meier curves. We then fit a longitudinal joint model to estimate risk of advanced neoplasia at each subsequent examination after baseline, adjusting for multiple colonoscopies within individuals.
resultsThrough 10 years of follow-up, there were 146 individuals among all baseline colonoscopy groups found to have at least 1 incident advanced neoplasia. The cumulative 10-year incidence of advanced neoplasia was highest among those with baseline CRC (43.7%; 95% CI 13.0%-74.4%), followed by those with baseline advanced adenoma (AA) (21.9%; 95% CI 15.7-28.1). The cumulative 10-year incidence of advanced neoplasia was 6.3% (95% CI 4.1%-8.5%) and 4.1% (95% CI 2.7%-5.4%) for baseline 1 to 2 small adenomas (<1cm, and without villous histology or high-grade dysplasia) and no neoplasia, respectively (log-rank P = .10). After adjusting for prior surveillance, the risk of advanced neoplasia at each subsequent examination was not significantly increased in veterans with 1 or 2 small adenomas at baseline (odds ratio 0.96; 95% CI 0.67-1.41) compared with veterans with no baseline neoplasia.
conclusionsBaseline screening colonoscopy findings associate with advanced neoplasia within 10 years. Individuals with only 1 or 2 small adenomas at baseline have a low risk of advanced neoplasia over 10 years. Alternative surveillance strategies, could be considered for these individuals.
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