Evidence map›Paper›PMID 31376049›Full record

Article3D printing in medicine2019

Customized tracheal design using 3D printing of a polymer hydrogel: influence of UV laser cross-linking on mechanical properties.

Ana Filipa Cristovão, David Sousa, Filipe Silvestre, Inês Ropio, Ana Gaspar, Célia Henriques, Alexandre Velhinho, Ana Catarina Baptista, Miguel Faustino, Isabel Ferreira

Abstract read
In one paragraph

Article in 3D printing in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Software for Bioprinting.International journal of bioprinting · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana Filipa Cristovãoi3N/CENIMAT, Department of Materials Science, Lisbon, Portugal.
David Sousai3N/CENIMAT, Department of Materials Science, Lisbon, Portugal.
Filipe SilvestreFAB-LAB, Lisbon, Portugal.
Inês Ropioi3N/CENIMAT, Department of Materials Science, Lisbon, Portugal.
Ana Gaspari3N/CENIMAT, Department of Materials Science, Lisbon, Portugal.
Célia Henriquesi3N/CENIMAT, Department of Materials Science, Lisbon, Portugal.
Alexandre Velhinhoi3N/CENIMAT, Department of Materials Science, Lisbon, Portugal.
Ana Catarina Baptistai3N/CENIMAT, Department of Materials Science, Lisbon, Portugal.
Miguel Faustinoi3N/CENIMAT, Department of Materials Science, Lisbon, Portugal.
Isabel Ferreirai3N/CENIMAT, Department of Materials Science, Lisbon, Portugal. imf@fct.unl.pt.ORCID http://orcid.org/0000-0002-8838-0364

Funding

FEDER funds through the COMPETE 2020 Program and National Funds through FCT - Portuguese Foundation for Science and Technology UID/CTM/50025/2013, UID/QUI/50006/2013 and Pest-UID/FIS/00068/2013H2020 European Research Council 647596H2020 Industrial Leadership TransFlexTeg-645241
6 · The paper itself

Abstract

backgroundThe use of 3D printing of hydrogels as a cell support in bio-printing of cartilage, organs and tissue has attracted much research interest. For cartilage applications, hydrogels as soft materials must show some degree of rigidity, which can be achieved by photo- or chemical polymerization. In this work, we combined chemical and UV laser polymeric cross-linkage to control the mechanical properties of 3D printed hydrogel blends. Since there are few studies on UV laser cross-linking combined with 3D printing of hydrogels, the work here reported offered many challenges.

methodsPolyethylene glycol diacrylate (PEGDA), sodium alginate (SA) and calcium sulphate (CaSO

resultsAt a laser density of 70 mW/cm

conclusionsWe printed a partial tracheal model using optimized printing conditions and proved that the materials and methods developed may be useful for printing of organ models to support surgery or even to produce customized tracheal implants, after further optimization.

Indexed as

3D printingBiopolymerIn-situ UV laser polymerizationMechanical propertiesTracheal 3D model

Identifiers

PMID31376049
PMCPMC6743139

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.