Trial reportLasers in medical science2020
Assessment of photobiomodulation therapy by an 8l0-nm diode laser on the reversal of soft tissue local anesthesia in pediatric dentistry: a preliminary randomized clinical trial.
Trial report in Lasers in medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Effect of 810-nm diode laser photobiomodulation on the reversal of maxillary and mandibular soft tissue local anaesthesia in children: a randomized split-mouth clinical trial.Scientific reports · 2026Trial
- Expediting the reversal of inferior alveolar nerve block anesthesia in children with photobiomodulation therapy.Lasers in medical science · 2024Trial
- Enhanced Recovery of Local Anesthesia in Pediatric Patients: The Impact of Photobiomodulation on Reversing Anesthesia Effects.Medical science monitor : international medical journal of experimental and clinical research · 2024Trial
- Evaluation of the effects of photobiomodulation with different laser application doses on injection pain in children: a randomized clinical trial.Lasers in medical science · 2022Trial
- Effectiveness of Low-level Laser Therapy on Reversing Soft-tissue Local Anesthesia among 5- to 8-year-old Children: A Randomized Split-mouth Clinical Trial.International journal of clinical pediatric dentistry · 2026Article
- Review
- Effectiveness of Diode Laser Treatment in Managing Dentin Hypersensitivity in Vietnamese Adults: A Six-Month Prospective Study.Clinical, cosmetic and investigational dentistry · 2026Article
- From Numbness to Comfort: Pioneering Pediatric Anesthesia Reversal with Photobiomodulation.International journal of clinical pediatric dentistry · 2025Review
- Effect of photo-bio-modulation on pain perception with inferior alveolar nerve block among children: A split mouth study.Bioinformation · 2025Article
- Effect of Low-Level Laser Therapy on Reversal of Soft Tissue Local Anesthesia in Children: A Randomized Clinical Trial.Journal of lasers in medical sciences · 2025Article
- The Comparison of 940nm and 810nm Diode Laser Effects on the Repair of Inferior Alveolar Sensory Nerve Injury: A Clinical Trial.Journal of dentistry (Shiraz, Iran) · 2024Article
- Comparative evaluation of photobiomodulation therapy at 660 and 810 nm wavelengths on the soft tissue local anesthesia reversal in pediatric dentistry: an in-vivo study.Journal of dental anesthesia and pain medicine · 2023Article
- Effect of Photobiomodulation Therapy With an 810-nm Diode Laser on Pain Perception Associated With Dental Injections in Children: A Double-Blind Randomized Controlled Clinical Trial.Journal of lasers in medical sciences · 2023Article
- Effect of Photobiomodulation Therapy following Direct Pulp Capping on Postoperative Sensitivity by Thermal Stimulus: A Retrospective Study.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2021Article
- The success of using 2% lidocaine in pain removal during extraction of mandibular premolars: a prospective clinical study.BMC oral health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the injection of local anesthesia in pediatric dental procedures, from the injection time until the elimination of tissue anesthesia, inevitable problems were reported. According to the encouraging results of previous studies addressing the positive effects of laser therapy on increasing the microcirculation, we aimed to investigate the clinical effect of photobiomodulation therapy on the reversal of soft tissue anesthesia in children. Using a split-mouth design, 34 children aged 4 to 8 years old, candidate for receiving local infiltration injection at both right and left side in mandible, were enrolled in the study. The mandibular right and left quadrants were randomly assigned to groups of laser or sham laser: in laser side, patients received 810-nm laser irradiation, and in the sham laser group, the patients had the laser in off mode at 45 min after injection with an interval of 7-10 days between two sessions of each quadrant treatments. The degree of anesthesia was evaluated using the palpation technique alternately every 15 min. Data were analyzed using paired sample t test and multiple linear regression test. The mean duration of anesthesia expressed in minutes was equal to 145.15 ± 23.27 and 188.82 ± 12.31 for the laser group and sham laser group, respectively. There was a significant difference in duration of anesthesia between two groups (P < 0.001). Considering the results and limitations of the present study, photobiomodulation therapy by 810-nm diode laser can be proposed as a non-invasive method in order to reduce the duration of anesthesia in pediatric patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.