ArticleSurgical endoscopy2020
Intraoperative assessment of esophageal motility using FLIP during myotomy for achalasia.
Article in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility.United European gastroenterology journal · 2025Guideline
- FLIP use in achalasia: comparing POEM and Heller myotomy outcomes: a systematic review and meta-analysis.Surgical endoscopy · 2025Pooled it
- Use of Endoflip - Impedance Planimetry System: For Which Indications?Visceral medicine · 2025Review
- A Software Framework for the Functional Lumen Imaging Probe-Mechanics (MechView).Neurogastroenterology and motility · 2025Article
- Endoscopic impedance planimetry versus high-resolution manometry (HRM) for pre-operative motility evaluation in anti-reflux surgery.Surgical endoscopy · 2024Article
- Role of short interval FLIP panometry in predicting long-term outcomes after per-oral endoscopic myotomy.Surgical endoscopy · 2023Article
- Changes in impedance planimetry (EndoFLIP) measurements at follow-up after peroral endoscopic myotomy (POEM).Surgical endoscopy · 2022Article
- Peroral Endoscopy Myotomy (POEM) for Esophageal Motility Disorders.Current gastroenterology reports · 2022Review
- The Predictive Value of Intraoperative Esophageal Functional Luminal Imaging Probe Panometry in Patients With Achalasia Undergoing Peroral Endoscopic Myotomy: A Single-center Experience.Journal of neurogastroenterology and motility · 2022Article
- Laparoscopic Heller Myotomy and Toupet Fundoplication.World journal of surgery · 2022Article
- Using a standardized intra-operative endoflip protocol during fundoplication to identify factors that affect distensibility.Surgical endoscopy · 2021Article
- Comparison of preoperative, intraoperative, and follow-up functional luminal imaging probe measurements in patients undergoing myotomy for achalasia.Gastrointestinal endoscopy · 2021Article
- Experience-based expert consensus on the intra-operative usage of the Endoflip impedance planimetry system.Surgical endoscopy · 2021Article
- Intraoperative FLIP distensibility during POEM varies according to achalasia subtype.Surgical endoscopy · 2021Article
- The Modern Age of POEM: the Past, Present and Future of Per-Oral Endoscopic Myotomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Review
- Comparison of peroral endoscopic myotomy between de-novo achalasia and achalasia with prior treatment.Surgical endoscopy · 2021Article
- Esophageal Functional Lumen Imaging Probe (FLIP): How Can FLIP Enhance Your Clinical Practice?Digestive diseases and sciences · 2020Review
- EndoFLIP in the Esophagus: Assessing Sphincter Function, Wall Stiffness, and Motility to Guide Treatment.Gastroenterology clinics of North America · 2020Review
- Applying the Functional Luminal Imaging Probe to Esophageal Disorders.Current gastroenterology reports · 2020Review
- Esophageal POEM: the new standard of care.Translational gastroenterology and hepatology · 2020Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe functional luminal imaging probe (FLIP) can evaluate esophagogastric junction (EGJ) distensibility and esophageal peristalsis in real time. FLIP measurements performed during diagnostic endoscopy can accurately discriminate between healthy controls and patients with achalasia based on EGJ-distensibility and distinct motility patterns termed repetitive antegrade contractions (RACs) and repetitive retrograde contractions (RRCs). We sought to evaluate real-time motility changes in patients undergoing surgical myotomy for achalasia.
methodsFLIP measurements using a stepwise volumetric distention protocol were performed at three time points during assessment and performance of laparoscopic Heller myotomy and POEM: (1) During preoperative outpatient endoscopy, (2) Intraoperatively following induction of anesthesia, and (3) Intraoperatively after myotomy completion. EGJ-distensibility, contractility, RACs, and RRCs were measured.
resultsFLIP measurements were performed in 32 patients. The EGJ-distensibility index was similar between the preoperative and initial operative measurements (1.1 vs 1.4 mm
conclusionsThis first report of real-time intraoperative measurement of esophageal motility using FLIP demonstrates the feasibility of such assessments during surgical myotomy for achalasia. Patients with type I and II achalasia exhibited rare intraoperative contractility, while the presence of motility was the norm in those with type III. Patients with type III achalasia demonstrated an immediate reduction in repetitive contraction motility patterns and contractile vigor following myotomy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.