ArticleRheumatology international2019
Malignancy risk in Korean male patients with ankylosing spondylitis.
Article in Rheumatology international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Risk of Hematologic Malignancies in Elderly Patients With Ankylosing Spondylitis: A Cohort Study and Systematic Review.Mayo Clinic proceedings · 2023Pooled it
- Age-Specific Risk Factors for Cancer in a Long-Term Korean Cohort of Patients with Ankylosing Spondylitis Treated with TNF Inhibitors.Journal of clinical medicine · 2025Article
- Non-steroidal anti-inflammatory drugs and risk of kidney cancer: A Swedish nationwide cohort study in the general and high-use populations.Journal of internal medicine · 2025Article
- Large-scale genome-wide association studies reveal the genetic causal etiology between ankylosing spondylitis and risk of leukemia and lymphocytic malignancies.Frontiers in oncology · 2024Article
- Incidence of cancer in chronic inflammatory demyelinating polyneuropathy: a nationwide cohort study in South Korea.Frontiers in neurology · 2024Article
- Increased oxidative and chromosomal DNA damage in patients with ankylosing spondylitis: its role in pathogenesis.Clinical and experimental medicine · 2023Article
- The Risk and Predictors of Malignancies in Ankylosing Spondylitis Patients in Israel-A Retrospective Electronic Data-Based Study.Journal of clinical medicine · 2023Article
- Diffuse large B-cell lymphoma presenting as sternal mass in a patient with ankylosing spondylitis: a case report study.Annals of medicine and surgery (2012) · 2023Article
- Malignancy in ankylosing spondylitis: a cross-sectional analysis of a large population database.BMC rheumatology · 2022Article
- Ankylosing Spondylitis and the Risk of Lung Cancer: A Meta-Analysis and Mendelian Randomization.Frontiers in genetics · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study is to determine the overall and specific cancer risks in male patients with ankylosing spondylitis (AS). From the claims database of the Health Insurance and Review Assessment, male patients with AS without prior cancer history were selected (n = 21,780). Stratified random samples of claims data were used as a reference general male population group (n = 342,361). Incidence rates of overall and types of cancer were presented as number of events per 10,000 person-years with 95% confidence interval (CI). A standardized incidence ratio (SIR) was used to represent the association between AS and cancer, accounting for person-years at risk. Compared to a general male population group, the overall incidence of cancer was increased in male patients with AS (SIR 1.25, 95% CI 1.15-1.36). For specific malignancy types, the risks of male reproductive system malignancy (SIR 1.97, 95% CI 1.59-2.35) and pancreatic cancer (SIR 1.75, 95% CI 1.12-2.37) were increased. Male patients with AS had increased cancer risk, especially for male reproductive system and pancreatic cancer.
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Registered trials
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