ArticleScientific reports2019
Examining the identification of age-related atrophy between T1 and T1 + T2-FLAIR cortical thickness measurements.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
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- Structural brain imaging biomarkers for predicting seizure recurrence after a first unprovoked seizure.Epilepsia open · 2026Article
- Differences in Cortical Morphology in People With and Without Migraine: A Registry for Migraine (REFORM) MRI Study.Neurology · 2024Article
- Defining Overlooked Structures Reveals New Associations between the Cortex and Cognition in Aging and Alzheimer's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Sex, gender diversity, and brain structure in early adolescence.Human brain mapping · 2024Article
- Differential diagnosis of neurodegenerative dementias with the explainable MRI based machine learning algorithm MUQUBIA.Scientific reports · 2023Article
- Links between Neuroanatomy and Neurophysiology with Turning Performance in People with Multiple Sclerosis.Sensors (Basel, Switzerland) · 2023Article
- Different MRI structural processing methods do not impact functional connectivity computation.Scientific reports · 2023Article
- Parsimonious model for mass-univariate vertexwise analysis.Journal of medical imaging (Bellingham, Wash.) · 2022Article
- Relationships between preoperative cortical thickness, postoperative electroencephalogram slowing, and postoperative delirium.British journal of anaesthesia · 2021Article
- Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study.British journal of anaesthesia · 2021Observational
- A unified framework for association and prediction from vertex-wise grey-matter structure.Human brain mapping · 2020Article
- Article
- Compensating cortical thickness for cortical folding-related variation.Imaging neuroscience (Cambridge, Mass.)Article
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10 authors.
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Abstract
Cortical thickness is traditionally derived from T1-weighted MRI images. Recent studies have shown an improvement in segmentation with the combination of T1 + T2-FLAIR images. MRI data from 54 adults (mean: 71 years, 65-81 years, 48% females) that are part of an ongoing cohort study were analyzed to investigate whether T1 + T2-FLAIR cortical thickness measurements were superior to those derived from T1-weighted images in identifying age-related atrophy. T1-weighted and T2-FLAIR MRI images were processed through FreeSurfer v6.0. Data was extracted using the Desikan-Killiany (DKT) atlas. FreeSurfer's GUI QDEC examined age-related atrophy. Nonparametric tests, effect sizes, and Pearson correlations examined differences between T1-only and T1 + T2-FLAIR cortical thickness data. These analyses demonstrated that T1 + T2-FLAIR processed images significantly improved the segmentation of gray matter (chi-square x
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