ArticleNature communications2019
TeraVR empowers precise reconstruction of complete 3-D neuronal morphology in the whole brain.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed.
- Semi-automatic geometrical reconstruction and analysis of filopodia dynamics in 4D two-photon microscopy images.BMC bioinformatics · 2026Article
- Confocal Airy beam oblique light-sheet tomography for brain-wide cell type distribution and morphology.Nature methods · 2025Article
- Automatic and accurate reconstruction of long-range axonal projections of single-neuron in mouse brain.eLife · 2025Article
- Virtual reality-augmented differentiable simulations for digital twin applications in surgical planning.Scientific reports · 2025Article
- Image enhancement network based on fiber topology-preserving multi-module fusion for neuron reconstruction.Biomedical optics express · 2025Article
- A Multi-Scale Neuron Morphometry Dataset from Peta-voxel Mouse Whole-Brain Images.Scientific data · 2025Article
- A neuronal imaging dataset for deep learning in the reconstruction of single-neuron axons.Frontiers in neuroinformatics · 2025Article
- CVR-BBI: an open-source VR platform for multi-user collaborative brain to brain interfaces.Bioinformatics (Oxford, England) · 2024Article
- Neuronal diversity and stereotypy at multiple scales through whole brain morphometry.Nature communications · 2024Article
- Collaborative augmented reconstruction of 3D neuron morphology in mouse and human brains.Nature methods · 2024Article
- Gapr for large-scale collaborative single-neuron reconstruction.Nature methods · 2024Article
- A hierarchically annotated dataset drives tangled filament recognition in digital neuron reconstruction.Patterns (New York, N.Y.) · 2024Article
- Connecto-informatics at the mesoscale: current advances in image processing and analysis for mapping the brain connectivity.Brain informatics · 2024Review
- u-track3D: Measuring, navigating, and validating dense particle trajectories in three dimensions.Cell reports methods · 2023Article
- Metaverse Wearables for Immersive Digital Healthcare: A Review.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- Whole human-brain mapping of single cortical neurons for profiling morphological diversity and stereotypy.Science advances · 2023Article
- Full-Spectrum Neuronal Diversity and Stereotypy through Whole Brain Morphometry.Research square · 2023Article
- Localization and Registration of 2D Histological Mouse Brain Images in 3D Atlas Space.Neuroinformatics · 2023Article
- BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets.Nature methods · 2023Article
- MiCellAnnGELo: annotate microscopy time series of complex cell surfaces with 3D virtual reality.Bioinformatics (Oxford, England) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
Abstract
Neuron morphology is recognized as a key determinant of cell type, yet the quantitative profiling of a mammalian neuron's complete three-dimensional (3-D) morphology remains arduous when the neuron has complex arborization and long projection. Whole-brain reconstruction of neuron morphology is even more challenging as it involves processing tens of teravoxels of imaging data. Validating such reconstructions is extremely laborious. We develop TeraVR, an open-source virtual reality annotation system, to address these challenges. TeraVR integrates immersive and collaborative 3-D visualization, interaction, and hierarchical streaming of teravoxel-scale images. Using TeraVR, we have produced precise 3-D full morphology of long-projecting neurons in whole mouse brains and developed a collaborative workflow for highly accurate neuronal reconstruction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.