Evidence map›Paper›PMID 31375306›Full record

ReviewJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia2019

Clinical neuroprosthetics: Today and tomorrow.

Morgan B Lee, Daniel R Kramer, Terrance Peng, Michael F Barbaro, Charles Y Liu, Spencer Kellis, Brian Lee

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Explainability in AI-enabled medical neurotechnology: a scoping review.Journal of neuroengineering and rehabilitation · 2026
    Article
  2. User-Centered Design of Neuroprosthetics: Advancements and Limitations.CNS & neurological disorders drug targets · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Morgan B LeeDepartment of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA; USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, CA, USA. Electronic address: morganle@usc.edu.
Daniel R KramerDepartment of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA; USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, CA, USA.
Terrance PengDepartment of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA; USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, CA, USA.
Michael F BarbaroDepartment of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA; USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, CA, USA.
Charles Y LiuDepartment of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA; USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, CA, USA; Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Spencer KellisDepartment of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA; USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, CA, USA; T&C Chen Brain Machine Interface Center, California Institute of Technology, Pasadena, CA, USA; Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Brian LeeDepartment of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA; USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, CA, USA; Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.

Funding

Mentored Career DevelopmentKL2TR001854 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Elizabeth Rhea Erwin Burner, Amy Elizabeth West · 2016 to 2026
$9.0M
NCATS NIH HHS KL2 TR001854
6 · The paper itself

Abstract

Implantable neurostimulation devices provide a direct therapeutic link to the nervous system and can be considered brain-computer interfaces (BCI). Under this definition, BCI are not simply science fiction, they are part of existing neurosurgical practice. Clinical BCI are standard of care for historically difficult to treat neurological disorders. These systems target the central and peripheral nervous system and include Vagus Nerve Stimulation, Responsive Neurostimulation, and Deep Brain Stimulation. Recent advances in clinical BCI have focused on creating "closed-loop" systems. These systems rely on biomarker feedback and promise individualized therapy with optimal stimulation delivery and minimal side effects. Success of clinical BCI has paralleled research efforts to create BCI that restore upper extremity motor and sensory function to patients. Efforts to develop closed loop motor/sensory BCI is linked to the successes of today's clinical BCI.

Indexed as

Brain-Computer InterfacesDeep Brain StimulationHumansNervous System DiseasesVagus Nerve Stimulation

Identifiers

PMID31375306
PMCPMC6717542

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.