Evidence map›Paper›PMID 31374976›Full record

Observational studyNutrients2019

The Safety and Impact of a Model of Intermittent, Time-Restricted Circadian Fasting ("Ramadan Fasting") on Hidradenitis Suppurativa: Insights from a Multicenter, Observational, Cross-Over, Pilot, Exploratory Study.

Giovanni Damiani, Naim Mahroum, Paolo Daniele Maria Pigatto, Alessia Pacifico, Piergiorgio Malagoli, Danica Tiodorovic, Rosalynn Rz Conic, Howard Amital, Nicola Luigi Bragazzi, Abdulla Watad and 1 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. The Role of Hormones in Hidradenitis Suppurativa: A Systematic Review.International journal of molecular sciences · 2022
    Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Dietary Factors and Hidradenitis Suppurativa.Dermatology and therapy · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Hidradenitis Suppurativa: Host-Microbe and Immune Pathogenesis Underlie Important Future Directions.JID innovations : skin science from molecules to population health · 2021
    Review
  18. Observational
  19. How Far Are We from Prescribing Fasting as Anticancer Medicine?International journal of molecular sciences · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 6 countries.

Giovanni DamianiDepartment of Dermatology, Case Western Reserve University, Cleveland, OH 44106, USA. robertobragazzi@gmail.com.
Naim MahroumSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel.
Paolo Daniele Maria PigattoClinical Dermatology, IRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy.
Alessia PacificoClinical Dermatology Department, San Gallicano Dermatological Institute, IRCCS, 00144 Rome, Italy.
Piergiorgio MalagoliDermatology Unit, Azienda Ospedaliera San Donato Milanese, 20097 Milan, Italy.
Danica TiodorovicDepartment of Dermatology, University of Nis, 18000 Nis, Serbia.
Rosalynn Rz ConicDepartment of Dermatology, Case Western Reserve University, Cleveland, OH 44106, USA.
Howard AmitalSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel.
Nicola Luigi BragazziPostgraduate School of Public Health, Department of Health Sciences, University of Genoa, 16132 Genoa, Italy. dr.giovanni.damiani@gmail.com.
Abdulla WatadSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel.
Mohammad AdawiSection of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds LS7 4SA, UK.
Tel Aviv University · ILBar-Ilan University · ILCase Western Reserve University · USCentro Studi GISED · ITIRCCS Policlinico San Donato · ITSan Gallicano Hospital · ITUniversity of Leeds · GBUniversity of Milan · ITUniversity of Nis · RSYork University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is a chronic-relapsing and debilitating disease, which affects the components of the folliculopilosebaceous unit and severely impacts on the perceived health-related quality of life. Among the possible treatments, dietary interventions, such as fasting, have been described to positively impact on HS. However, nothing is known about the effects of circadian, intermittent fasting, such as the Ramadan fasting. A sample of 55 HS patients (24 males (43.6%) and 31 females (56.4%), mean age 39.65 ± 8.39 years, average disease duration 14.31 ± 7.03 years) was recruited in the present study. The "Severity of International Hidradenitis Suppurativa Severity Score System" (IHS4) decreased significantly from 11.00 ± 5.88 (before Ramadan) to 10.15 ± 6.45 (after Ramadan), with a mean difference of -0.85 ± 0.83 (

Indexed as

Circadian RhythmFastingFeeding BehaviorIslamAdultCross-Over StudiesEuropeFemaleHidradenitis SuppurativaHumansMaleMiddle AgedPilot ProjectsRemission InductionRetrospective StudiesSeverity of Illness Indexcircadian rhythmsdietary interventionhidradenitis suppurativahuman biological clockintermittent fasting

Identifiers

PMID31374976
PMCPMC6722961
OpenAlexW2966780811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.