ReviewMarine drugs2019
Conversion of Chitin to Defined Chitosan Oligomers: Current Status and Future Prospects.
Review in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 168 citations in OpenAlex.
- Efficacy of chitinases from mangrove wetland derivedFrontiers in microbiology · 2026Article
- Chitosan based smart injectable hydrogels for biomedical applications: A comprehensive review.Bioactive materials · 2026Review
- Application of chitosan-based nanogels for dermal and transdermal delivery systems.Journal of materials science. Materials in medicine · 2025Review
- Rational Design and One-Step Immobilization of Chitosanase for Specific and Recyclable Chitobiose Production.Foods (Basel, Switzerland) · 2025Article
- Analysis, Properties, and Applications of Insect-Derived Chitosan: A Sustainable Path to Functional Polysaccharide Materials.Gels (Basel, Switzerland) · 2025Review
- Bone Defect Treatment in Regenerative Medicine: Exploring Natural and Synthetic Bone Substitutes.International journal of molecular sciences · 2025Review
- Chitosan processing waste nutrients compounds as a potential natural poultry premix.Journal of advanced veterinary and animal research · 2025Article
- Valorization of fishery industry waste: Chitosan extraction and its application in the industry.MethodsX · 2024Review
- Review
- Recent Advances in the Preparation, Antibacterial Mechanisms, and Applications of Chitosan.Journal of functional biomaterials · 2024Review
- Isolation and Structure Analysis of Chitin Obtained from Different Developmental Stages of the Mulberry Silkworm (Molecules (Basel, Switzerland) · 2024Article
- Insights into Chitin-Degradation Potential ofMicroorganisms · 2024Article
- A new strain ofFrontiers in microbiology · 2024Article
- Chitin-enriched insect frass fertilizer as a biorational alternative for root-knot nematode (Frontiers in plant science · 2024Article
- Biochemical Properties of a Cold-Active Chitinase from MarineMarine drugs · 2023Article
- Physicochemical Characterization and Antimicrobial Analysis of Vegetal Chitosan Extracted from Distinct Forest Fungi Species.Polymers · 2023Article
- Chitosan Based Materials in Cosmetic Applications: A Review.Molecules (Basel, Switzerland) · 2023Review
- A Novel Approach, Based on the Combined Action of Chitosan Hydrogel and Laccases, for the Removal of Dyes from Textile Industry Wastewaters.Gels (Basel, Switzerland) · 2023Article
- Chitosan and chito-oligosaccharide: a versatile biopolymer with endless grafting possibilities for multifarious applications.Frontiers in bioengineering and biotechnology · 2023Review
- Encapsulation with Natural Polymers to Improve the Properties of Biostimulants in Agriculture.Plants (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chitin is an abundant polysaccharide primarily produced as an industrial waste stream during the processing of crustaceans. Despite the limited applications of chitin, there is interest from the medical, agrochemical, food and cosmetic industries because it can be converted into chitosan and partially acetylated chitosan oligomers (COS). These molecules have various useful properties, including antimicrobial and anti-inflammatory activities. The chemical production of COS is environmentally hazardous and it is difficult to control the degree of polymerization and acetylation. These issues can be addressed by using specific enzymes, particularly chitinases, chitosanases and chitin deacetylases, which yield better-defined chitosan and COS mixtures. In this review, we summarize recent chemical and enzymatic approaches for the production of chitosan and COS. We also discuss a design-of-experiments approach for process optimization that could help to enhance enzymatic processes in terms of product yield and product characteristics. This may allow the production of novel COS structures with unique functional properties to further expand the applications of these diverse bioactive molecules.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.