Evidence map›Paper›PMID 31374914›Full record

ArticleNutrients2019

Vitamin D Status and Indices of Mineral Homeostasis in the Population: Differences Between 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D.

Massimo Cirillo, Giancarlo Bilancio, Ermanno Guarino, Pierpaolo Cavallo, Cinzia Lombardi, Simona Costanzo, Amalia De Curtis, Augusto Di Castelnuovo, Licia Iacoviello

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Vitamin D: A Bridge between Kidney and Heart.Life (Basel, Switzerland) · 2024
    Review
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Observational
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Massimo CirilloDepartment of Public Health, University of Naples "Federico II", 80131 Naples (NA), Italy. massimo.cirillo@unina.it.ORCID 0000-0002-6409-3504
Giancarlo BilancioDepartment of Medicine, Surgery and Odontoiatry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi (SA), Italy.
Ermanno GuarinoDepartment of Medicine, Surgery and Odontoiatry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi (SA), Italy.
Pierpaolo CavalloDepartment of Physics, University of Salerno, 84084 Fisciano (SA), Italy.ORCID 0000-0003-3111-5241
Cinzia LombardiMaternal-Infant Department, Hospital "San Pio", 82028 Benevento (BN), Italy.
Simona CostanzoDepartement of Epidemiology and Prevention, IRCCS Neuromed, 86077 Pozzilli (IS), Italy.ORCID 0000-0003-4569-1186
Amalia De CurtisDepartement of Epidemiology and Prevention, IRCCS Neuromed, 86077 Pozzilli (IS), Italy.ORCID 0000-0001-5104-0318
Augusto Di CastelnuovoMediterranea Cardiocentro, 80133 Napoli (NA), Italy.ORCID 0000-0001-9767-7998
Licia IacovielloDepartement of Epidemiology and Prevention, IRCCS Neuromed, 86077 Pozzilli (IS), Italy.ORCID 0000-0003-0514-5885
University of Salerno · ITIstituto Neurologico Mediterraneo · ITClinica Mediterranea · ITUniversity of Insubria · ITUniversity of Naples Federico II · IT

Funding

Agenzia Spaziale Italiana (Rome, Italy) 2013-093-R.0Instrumentation Laboratory (Milan, Italy) N/AItalian Ministry of University and Research (Rome, Italy) N/Aundefined <span style="color:gray;font-size:10px;">undefined</span> n/a
6 · The paper itself

Abstract

Opinions are conflicting about the epidemiology of vitamin D deficiency. This population-based study investigated cross-sectionally the associations of 25-hydroxyvitamin D (calcidiol) and 1,25-dihydroxyvitamin D (calcitriol) with indices of mineral homeostasis. Study cohort consisted of 979 persons of the Moli-Sani study, both sexes, ages ≥35 years. Data collection included serum calcidiol by different assays, serum calcitriol, serum parathyroid hormone, serum and urine calcium, and phosphorus. Prevalence of mild-to-moderate calcidiol deficiency (10-19 ng/mL) was 36.4% and did not associate with hypocalcemia or hyperparathyroidism. Prevalence of severe calcidiol deficiency (<10 ng/mL) was 16.8% and associated with hyperparathyroidism only (odds ratio = 8.81, 95% confidence interval = 2.4/32.9). Prevalence of calcitriol deficiency (<18 pg/mL) was 3.1% and associated with hypocalcemia (29.1, 7.4/114.5) but not hyperparathyroidism. In ANOVA along concentration strata, lower calcidiol associated with higher parathyroid hormone only (

Indexed as

AdultAgedBiomarkersCalciumCross-Sectional StudiesFemaleHomeostasisHumansHyperparathyroidismHypocalcemiaItalyMaleMiddle AgedParathyroid HormonePrevalenceProspective Studies1,25-dihydroxyvitamin D25-hydroxyvitamin DBiomarkersCalciumParathyroid HormonePTH protein, humanVitamin D1,25-dihydroxyvitamin D (calcitriol)25-hydroxyvitamin D (calcidiol)calciumepidemiologyparathyroid hormonephosphorus

Identifiers

PMID31374914
PMCPMC6722609
OpenAlexW2966490370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.