Evidence map›Paper›PMID 31374881›Full record

ReviewMolecules (Basel, Switzerland)2019

Mammalian DNA Polymerase Kappa Activity and Specificity.

Hannah R Stern, Jana Sefcikova, Victoria E Chaparro, Penny J Beuning

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Mitomycin C-induced DNA double-strand breaks are enhanced by catalytical inactivation of DNA polymerase κ in mice.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2025
    Article
  8. Article
  9. Activity of DNA polymerase κ across the genome in human fibroblasts.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hannah R SternDepartment of Chemistry & Chemical Biology, Northeastern University, Boston, MA 02115, USA.
Jana SefcikovaDepartment of Chemistry & Chemical Biology, Northeastern University, Boston, MA 02115, USA.
Victoria E ChaparroDepartment of Chemistry & Chemical Biology, Northeastern University, Boston, MA 02115, USA.
Penny J BeuningDepartment of Chemistry & Chemical Biology, Northeastern University, Boston, MA 02115, USA. p.beuning@neu.edu.ORCID 0000-0002-7770-022X
Northeastern University · US

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
Dynamics of Processivity Clamp Proteins in Bacterial DNA ReplicationR01GM123239 · NIGMS · NORTHEASTERN UNIVERSITY · PI BEUNING, PENNY J, KORZHNEV, DMITRY M. · 2017 to 2021
$1.8M
American Chemical Society Project SEEDNational Science Foundation MCB-1615946NIGMS NIH HHS P41 GM103311NIH HHS R01GM123239
6 · The paper itself

Abstract

DNA polymerase (pol) kappa is a Y-family translesion DNA polymerase conserved throughout all domains of life. Pol kappa is special6 ized for the ability to copy DNA containing minor groove DNA adducts, especially

Indexed as

DNA AdductsDNA DamageDNA-Directed DNA PolymeraseDNA ReplicationG-QuadruplexesHumansMutagenesisY-Family DNA PolymerasesDNA AdductsDNA-Directed DNA PolymerasePOLK protein, humanY-Family DNA Polymeraseschemotherapy resistanceDNA damageDNA replicationprimer extensiontranslesion DNA synthesisY-family

Identifiers

PMID31374881
PMCPMC6695781
OpenAlexW2966409534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.