SynthesisMedicine2019
Antenatal infection and intraventricular hemorrhage in preterm infants: A meta-analysis.
Synthesis in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Randomized trial of azithromycin to eradicate Ureaplasma respiratory colonization in preterm infants: 2-year outcomes.Pediatric research · 2022Trial
- The association of chorioamnionitis with intraventricular hemorrhage and long-term outcome in very preterm neonates.Frontiers in pediatrics · 2026Article
- Article
- Intraventricular haemorrhage, associated factors and mortality among very low birth weight neonates admitted at Muhimbili National Hospital, Dar es Salaam, Tanzania: a prospective cohort study.Italian journal of pediatrics · 2025Article
- Intraventricular hemorrhage among very low birth weight infants in a South African cohort: a retrospective study of trends & short-term outcomes.BMC pediatrics · 2025Article
- Identifying causes and associated factors of stillbirths using autopsy of the fetus and placenta.Archives of gynecology and obstetrics · 2025Observational
- Development and validation of a clinical features-based nomogram for predicting neonatal cerebral microbleeds.Quantitative imaging in medicine and surgery · 2025Article
- Development of a machine learning model for prediction of intraventricular hemorrhage in premature neonates.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Risk factors associated with intraventricular hemorrhage in very-low-birth-weight premature infants.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Impact of maternal infection on outcomes in extremely preterm infants.Pediatric research · 2024Article
- Review
- Risk factors for periventricular-intraventricular haemorrhage severity in preterm infants: a propensity score-matched analysis.BMC pediatrics · 2023Article
- Clinical Feature and General Management of Post-Hemorrhagic Hydrocephalus in Premature Infants.Journal of Korean Neurosurgical Society · 2023Article
- Predicting the likelihood of lower respiratory tractArchives of disease in childhood. Fetal and neonatal edition · 2023Article
- Review on the application of imaging examination for brain injury in premature infants.Frontiers in neurology · 2023Review
- Turkish Neonatal Society Guideline on the Diagnosis and Management of Germinal Matrix Hemorrhage-Intraventricular Hemorrhage and Related Complications.Turkish archives of pediatrics · 2021Article
- Maternal VaginalChildren (Basel, Switzerland) · 2021Article
- Risk factors for the deterioration of periventricular-intraventricular hemorrhage in preterm infants.Scientific reports · 2020Article
- ECMO for Neonatal Sepsis in 2019.Frontiers in pediatrics · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to summarize current evidence evaluating the association between antenatal infection and intraventricular hemorrhage (IVH) in preterm infants. MATERIALS AND
methodsWe searched for published articles on antenatal infection and IVH in 3 English (PubMed, the Cochrane Library, and EBSCO) and 3 Chinese (VEIPU, CNKI, and WANFANG) databases on May 19, 2019. In addition, the references of these articles were screened. The included studies had to meet all of the following criteria: preterm infants (<37 weeks); comparing antenatal infection with no infection; the outcomes included IVH (all grades), mild IVH, or sereve IVH; the type of study was randomized controlled trial or cohort study.
resultsA total of 23 cohort studies involving 13,605 preterm infants met our inclusion criteria. Antenatal infection increased the risk of IVH (odds ratios ([OR] 2.18, 95% confidence intervals [CI] 1.58-2.99), mild IVH (OR 1.95, 95% CI 1.09-3.49) and severe IVH (OR 2.65, 95% CI 1.52-4.61). For type of antenatal infection, the ORs and 95% CI were as follows: 2.21 (1.60-3.05) for chorioamnionitis, 2.26 (1.55-3.28) for histologic chorioamnionitis, 1.88 (1.22-2.92) for clinical chorioamnionitis, and 1.88 (1.14-3.10) for ureaplasma.
conclusionsAntenatal infection may increase the risk of developing IVH in the preterm infant. The evidence base is however of low quality and well-designed studies are needed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.