SynthesisHuman vaccines & immunotherapeutics2020
The clinical and economic burden of varicella in the Middle East: a systematic literature review.
Synthesis in Human vaccines & immunotherapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Varicella-zoster virus seroprevalence among reproductive-age women in Iran: a meta-analysis and implications for targeted immunization.BMC infectious diseases · 2025Pooled it
- Geographic and age-specific trends in vaccine-preventable diseases in Qatar: A primary health care-based study (2021-2024).Qatar medical journal · 2026Article
- Evaluation of Pediatric Patients Diagnosed with Encephalitis: Single Center Experience.Sisli Etfal Hastanesi tip bulteni · 2026Article
- The Burden of Skin and Subcutaneous Diseases in North Africa and the Middle East (NAME) From 1990 to 2021.International journal of dermatology · 2025Article
- Seroprevalence and Vaccination Determinants of Varicella Zoster Virus Among Pediatric and Adolescent Populations in Northern Lebanon.Vaccines · 2025Article
- Severe skin complications of varicella in previously healthy children in Iran: emerging concern.BMC infectious diseases · 2025Article
- Seroprevalence of Varicella-Zoster Virus and the Need for Herpes Zoster Vaccination Among Adults in Saudi Arabia.Cureus · 2025Article
- Silent reactivation of Varicella Zoster virus in hemodialysis patients.: A management dilemma.Saudi medical journal · 2024Article
- Immunity to Varicella Zoster Virus in Healthcare Workers: A Systematic Review and Meta-Analysis (2024).Vaccines · 2024Review
- Article
- Epidemiology of Varicella Zoster Virus and Herpes Zoster Virus in Gulf Cooperation Council Countries: A Review of the Literature.Infectious diseases and therapy · 2023Review
- Clinical efficacy and effectiveness of alternative varicella vaccination strategies: An overview of reviews.Reviews in medical virology · 2023Review
- Global varicella vaccination programs.Clinical and experimental pediatrics · 2022Article
- Acceptance of varicella vaccination.Human vaccines & immunotherapeutics · 2021Article
- Multicenter prospective surveillance study of viral agents causing meningoencephalitis.Scientific reports · 2021Observational
- Epidemiological health assessment in primary healthcare in the State of Qatar- 2019.Qatar medical journal · 2021Article
Corrections and comments
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Authors and funding
10 authors at 8 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This systematic literature review was conducted to better understand the epidemiology and burden of varicella across the Middle East, gain insight into the evidence to support using universal varicella vaccination (UVV), and identify potential data gaps. Both epidemiology and economic data on the burden of varicella were limited and varied significantly. Most of the data focussed on varicella burden in the absence of a UVV program. In the absence of UVV, varicella incidence is increasing across this region with varicella infection associated with substantial morbidity. Although limited, data on the impact of vaccination at a population level indicated UVV programs reduce varicella incidence and hospitalizations, in line with global experience. Further research and action are needed to better understand varicella epidemiology in the Middle East, increase awareness and understanding in the region, and provide local data to support national public-health decisions regarding the implementation of UVV programs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.