ArticleVeterinary medicine and science2019
Genetic basis of voluntary water consumption in two divergently selected strains of inbred mice.
Article in Veterinary medicine and science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 citations in OpenAlex.
- Contribution of murine strain background to NabioRxiv : the preprint server for biology · 2026Article
- Genetic basis of voluntary water consumption in two divergently selected strains of inbred mice.Veterinary medicine and science · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInbred mouse strains with normal renal function show a substantial difference in daily water consumption across strains. This study uses two strains of inbred mice C57BR/CDJ (BR), which are high consumers, and C57BL/10J (BL), which are low consumers, their reciprocal F
methodsThe effective number of genes controlling water consumption was estimated using the Castle-Wright estimator. Additive and dominance genotypic values as well as the degree of dominance were calculated using estimated strain means.
resultsAccording to Castle-Wright, a minimum of 10 factors were estimated to affect the difference in consumption across the two strains. Between seven and eight are expected to be high effect factors. Using the Zeng adjustment, it was determined that 30-40 factors potentially affect the difference in consumption.
conclusionsThese numbers were surprising but may be related to several sources of variation present in the BR strain. A negative degree of dominance indicated the BL strain has more dominant factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.