Evidence map›Paper›PMID 31373756›Full record

ArticleDepression and anxiety2019

Advancing clinical neuroscience through enhanced tools: Pediatric social anxiety as an example.

Ashley R Smith, Katharina Kircanski, Melissa A Brotman, Quyen B Do, Anni R Subar, Jennifer S Silk, Scott Engel, Ross D Crosby, Anita Harrewijn, Lauren K White and 6 more

Abstract read
In one paragraph

Article in Depression and anxiety, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  8. Sleepless nights, sour moods: daily sleep-irritability links in a pediatric clinical sample.Journal of child psychology and psychiatry, and allied disciplines · 2024
    Article
  9. Threat Appraisal and Pediatric Anxiety: Proof of Concept of a Latent Variable Approach.Clinical psychological science : a journal of the Association for Psychological Science · 2024
    Article
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  17. The prefrontal cortex, pathological anxiety, and anxiety disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ashley R SmithEmotion and Development Branch, National Institute of MentalHealth, Bethesda, Maryland.ORCID 0000-0002-2909-8756
Katharina KircanskiEmotion and Development Branch, National Institute of MentalHealth, Bethesda, Maryland.
Melissa A BrotmanEmotion and Development Branch, National Institute of MentalHealth, Bethesda, Maryland.
Quyen B DoDepartment of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Anni R SubarEmotion and Development Branch, National Institute of MentalHealth, Bethesda, Maryland.
Jennifer S SilkDepartment of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Scott EngelCenter for Bio-Behavioral Research, Sanford Research, Fargo, North Dakota.
Ross D CrosbyCenter for Bio-Behavioral Research, Sanford Research, Fargo, North Dakota.
Anita HarrewijnEmotion and Development Branch, National Institute of MentalHealth, Bethesda, Maryland.
Lauren K WhiteLifespan Brain Institute, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Simone P HallerEmotion and Development Branch, National Institute of MentalHealth, Bethesda, Maryland.
Elise M CardinaleEmotion and Development Branch, National Institute of MentalHealth, Bethesda, Maryland.
George A BuzzellDepartment of Education, University of Maryland, College Park, Maryland.
Tyson BarkerDepartment of Psychology, University of Oregon, Eugene, Oregon.
Ellen LeibenluftEmotion and Development Branch, National Institute of MentalHealth, Bethesda, Maryland.
Daniel S PineEmotion and Development Branch, National Institute of MentalHealth, Bethesda, Maryland.

Funding

Intramural NIH HHS Z99 MH999999
6 · The paper itself

Abstract

backgroundClinical researchers face challenges when trying to quantify diverse processes engaged during social interactions. We report results from two studies, each demonstrating the potential utility of tools for examining processes engaged during social interactions.

methodIn the first study, youth (n = 57) used a smartphone-based tool to rate mood and responses to social events. A subset (n = 20) completed the second, functional magnetic resonance imaging study. This second study related anxiety to error-evoked brain responses in two social conditions-while being observed and when alone. We also combined these tools to bridge clinical, social-contextual, and neural levels of measurement.

resultsResults from the first study showed an association between negatively-perceived social experiences and a range of negative emotions. In the second study there was a positive correlation during error monitoring between social-anxiety severity and context-specific activation of the pregenual anterior cingulate cortex. Finally, during imaging, the perceived quality of peer interactions as assessed using the smartphone-based tool, interacted with social context to predict levels of activation in the hippocampus and superior frontal gyrus.

conclusionsBy improving measurement, enhanced tools may provide new means for studying relationships among anxiety, brain function, and social interactions.

Indexed as

Interpersonal RelationsAdolescentBrainBrain MappingChildFearFemaleHumansMagnetic Resonance ImagingMalePhobia, SocialSmartphoneadolescentanxietyecological momentary assessmentneuroimagingsocial phobia

Identifiers

PMID31373756
PMCPMC9589399

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.