Evidence map›Paper›PMID 31373604›Full record

ArticleBioinformatics (Oxford, England)2020

RAG-Web: RNA structure prediction/design using RNA-As-Graphs.

Grace Meng, Marva Tariq, Swati Jain, Shereef Elmetwaly, Tamar Schlick

Open access · greenAbstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Heterogeneous and multiple conformational transition pathways between pseudoknots of the SARS-CoV-2 frameshift element.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Grace MengDepartment of Chemistry, New York University, New York, NY 10003, USA.
Marva TariqDepartment of Chemistry, Smith College, Northampton, MA 01063, USA.
Swati JainDepartment of Chemistry, New York University, New York, NY 10003, USA.
Shereef ElmetwalyDepartment of Chemistry, New York University, New York, NY 10003, USA.
Tamar SchlickDepartment of Chemistry, New York University, New York, NY 10003, USA.
New York University · USSmith College · US

Funding

Bridging Disparate Structural/Functional Scales: Multiscale Modeling of the Chromatin Fiber and RNA Tertiary StructuresR35GM122562 · NIGMS · NEW YORK UNIVERSITY · PI Tamar Schlick · 2017 to 2026
$4.6M
NIGMS NIH HHS R35 GM122562
6 · The paper itself

Abstract

summaryWe launch a webserver for RNA structure prediction and design corresponding to tools developed using our RNA-As-Graphs (RAG) approach. RAG uses coarse-grained tree graphs to represent RNA secondary structure, allowing the application of graph theory to analyze and advance RNA structure discovery. Our webserver consists of three modules: (a) RAG Sampler: samples tree graph topologies from an RNA secondary structure to predict corresponding tertiary topologies, (b) RAG Builder: builds three-dimensional atomic models from candidate graphs generated by RAG Sampler, and (c) RAG Designer: designs sequences that fold onto novel RNA motifs (described by tree graph topologies). Results analyses are performed for further assessment/selection. The Results page provides links to download results and indicates possible errors encountered. RAG-Web offers a user-friendly interface to utilize our RAG software suite to predict and design RNA structures and sequences. AVAILABILITY AND IMPLEMENTATION: The webserver is freely available online at: http://www.biomath.nyu.edu/ragtop/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

Databases, Nucleic AcidRNAAlgorithmsNucleic Acid ConformationSoftwareRNA

Identifiers

PMID31373604
PMCPMC7999136
OpenAlexW2966773397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.