ArticleJournal of veterinary internal medicine2020
Clinical utility of estimation of glomerular filtration rate in dogs.
Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Preliminary study investigating the role of estimated glomerular filtration rate, proteinuria and hypertension to inform on chronic kidney disease after acute kidney injury.The Journal of small animal practice · 2026Article
- Survival outcomes and prognostic indicators in canine pancreatitis: A retrospective cohort study of acute kidney injury and concurrent diseases.Veterinary world · 2025Article
- Levopositioned caudal vena cava and circumcaval left ureter with subsequent hydronephrosis and hydroureter in a dog.Veterinary medicine and science · 2024Article
- Early Detection of Chronic Kidney Disease Using Plasma Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 in Small-Breed Dogs: A Retrospective Pilot Study.Animals : an open access journal from MDPI · 2024Article
- A comprehensive analysis of albuminuria in canine chronic kidney disease.Veterinary medicine and science · 2024Article
- Effect of standard-dose and high-dose pimobendan on select indices of renal and cardiac function in dogs with American College of Veterinary Internal Medicine stage B2 myxomatous mitral valve disease.Journal of veterinary internal medicine · 2022Article
- Drug-Dosing Adjustment in Dogs and Cats with Chronic Kidney Disease.Animals : an open access journal from MDPI · 2022Review
- A Review of Specific Biomarkers of Chronic Renal Injury and Their Potential Application in Nonclinical Safety Assessment Studies.Toxicologic pathology · 2021Review
- Population Pharmacokinetics of Intravenous Amoxicillin Combined With Clavulanic Acid in Healthy and Critically Ill Dogs.Frontiers in veterinary science · 2021Article
- Association between breed and renal biomarkers of glomerular filtration rate in dogs.The Veterinary record · 2020Article
- Hypertension, retinopathy, and acute kidney injury in dogs: A prospective study.Journal of veterinary internal medicine · 2020Article
- Clinical utility of estimation of glomerular filtration rate in dogs.Journal of veterinary internal medicine · 2020Article
- Relationship between serum iohexol clearance, serum SDMA concentration, and serum creatinine concentration in non-azotemic dogs.Journal of veterinary internal medicine · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlomerular filtration rate (GFR) estimation is the gold standard for assessment of renal function, although the clinical utility of this test is unclear.
objectivesTo describe the clinical utility of GFR estimation in dogs. ANIMALS: Medical records of 132 dogs that had serum iohexol clearance measured between 2012 and 2017.
methodsIohexol clearance and clinical records were reviewed and submitting practices contacted to obtain outcome data. Dogs were classified into 4 groups based on the reason for performing GFR estimation: A1 (screening for pre-azotemic chronic kidney disease [CKD], n = 105), A2 (confirmation of azotemic CKD, n = 3), B (screening for pre-azotemic acute kidney injury, n = 19), and C (miscellaneous causes, n = 5). Descriptive review of the clinical utility of GFR estimation is provided.
resultsFor dogs in Group A1, renal disease was diagnosed in 9/9 dogs with a GFR ≥40% decreased below the mean GFR of their body weight category, in 5/6 dogs with a ≥30% but <40% reduction in GFR and in 7/9 dogs with a ≥20% but <30% reduction in GFR. CONCLUSIONS AND CLINICAL IMPORTANCE: Glomerular filtration rate estimation is useful for the diagnosis of CKD before the onset of azotemia.
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