ArticleJournal of medical Internet research2019
Exploring the Relationship Between Usage and Outcomes of an Internet-Based Intervention for Individuals With Depressive Symptoms: Secondary Analysis of Data From a Randomized Controlled Trial.
Article in Journal of medical Internet research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effectiveness of Internet-delivered treatment for generalized anxiety disorder: An updated systematic review and meta-analysis.Depression and anxiety · 2021Pooled it
- Efficacy of a self-guided online resilience intervention for improving mental health among university students: A randomized controlled trial.Scientific reports · 2026Trial
- Correlates of Engagement and Associations With Outcomes in a Cannabis Harm-Reduction Mobile App for Youth With First-Episode Psychosis: Exploratory Analysis of the CHAMPS Pilot Randomized Controlled Trial.JMIR formative research · 2026Trial
- Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2).Health technology assessment (Winchester, England) · 2025Trial
- Statistical methods to adjust for the effects on intervention compliance in randomized clinical trials where precision treatment rules are being developed.International journal of methods in psychiatric research · 2025Trial
- Internet-delivered cognitive behavior therapy versus treatment as usual for anxiety and depression among Latin American university students: A randomized clinical trial.Journal of consulting and clinical psychology · 2023Trial
- Trajectories of Symptoms in Digital Interventions for Depression and Anxiety Using Routine Outcome Monitoring Data: Secondary Analysis Study.JMIR mHealth and uHealth · 2023Trial
- A Randomized Controlled Trial of Internet-Based Self-Help for Stress During the COVID-19 Pandemic.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2022Trial
- Long-term Effects of a Social Media-Based Intervention (Run4Love) on Depressive Symptoms of People Living With HIV: 3-Year Follow-up of a Randomized Controlled Trial.Journal of medical Internet research · 2022Trial
- Trial
- Dose-Response Effects of Patient Engagement on Health Outcomes in an mHealth Intervention: Secondary Analysis of a Randomized Controlled Trial.JMIR mHealth and uHealth · 2022Trial
- A Digital Self-management Program (Help to Overcome Problems Effectively) for People Living With Cancer: Feasibility Randomized Controlled Trial.Journal of medical Internet research · 2021Trial
- An internet-delivered self-management programme for bipolar disorder in mental health services in Ireland: Results and learnings from a feasibility trial.Clinical psychology & psychotherapy · 2020Trial
- Relationship Between Patient Engagement and Depressive Symptoms Among People Living With HIV in a Mobile Health Intervention: Secondary Analysis of a Randomized Controlled Trial.JMIR mHealth and uHealth · 2020Trial
- Predictors and Effects of Usage of an Online Mindfulness Intervention for Distressed Cancer Patients: Usability Study.Journal of medical Internet research · 2020Trial
- The Impact of Text Engagement in a Brief, Technology-Enhanced Adjunctive Intervention for Youth Suicide Risk and Depression.American journal of psychotherapy · 2026Article
- Efficacy of a video-viewing intervention of smartphone-based positive word stimulation on depressive symptoms in individuals with subthreshold depression: Protocol for a randomized controlled trial.PCN reports : psychiatry and clinical neurosciences · 2026Article
- Developing a Behavioral Phenotyping Layer for Artificial Intelligence-Driven Predictive Analytics in a Digital Resiliency Course: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
- Behavioral engagement patterns and psychosocial outcomes in web-based interpretation bias training for anxiety.PLOS digital health · 2025Article
- A Mobile App-Based Intervention (Parentbot-a Digital Healthcare Assistant) for Parents: Secondary Analysis of a Randomized Controlled Trial.Journal of medical Internet research · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInternet interventions can easily generate objective data about program usage. Increasingly, more studies explore the relationship between usage and outcomes, but they often report different metrics of use, and the findings are mixed. Thus, current evaluations fail to demonstrate which metrics should be considered and how these metrics are related to clinically meaningful change.
objectiveThis study aimed to explore the relationship between several usage metrics and outcomes of an internet-based intervention for depression.
methodsThis is a secondary analysis of data from a randomized controlled trial that examined the efficacy of an internet-based cognitive behavioral therapy for depression (Space from Depression) in an adult community sample. All participants who enrolled in the intervention, regardless of meeting the inclusion criteria, were included in this study. Space from Depression is a 7-module supported intervention, delivered over a period of 8 weeks. Different usage metrics (ie, time spent, modules and activities completed, and percentage of program completion) were automatically collected by the platform, and composite variables from these (eg, activities per session) were computed. A breakdown of the usage metrics was obtained by weeks. For the analysis, the sample was divided into those who obtained a reliable change (RC)-and those who did not.
resultsData from 216 users who completed pre- and posttreatment outcomes were included in the analyses. A total of 89 participants obtained an RC, and 127 participants did not obtain an RC. Those in the RC group significantly spent more time, had more log-ins, used more tools, viewed a higher percentage of the program, and got more reviews from their supporter compared with those who did not obtain an RC. Differences between groups in usage were observed from the first week in advance across the different metrics, although they vanished over time. In the RC group, the usage was higher during the first 4 weeks, and then a significant decrease was observed. Our results showed that specific levels of platform usage, 7 hours total time spent, 15 sessions, 30 tools used, and 50% of program completion, were associated with RC.
conclusionsOverall, the results showed that those individuals who obtained an RC after the intervention had higher levels of exposure to the platform. The usage during the first half of the intervention was higher, and differences between groups were observed from the first week. This study also showed specific usage levels associated with outcomes that could be tested in controlled studies to inform the minimal usage to establish adherence. These results will help to better understand how to use internet-based interventions and what optimal level of engagement can most affect outcomes.
trial registrationISRCTN Registry ISRCTN03704676; http://www.isrctn.com/ISRCTN03704676. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1186/1471-244X-14-147.
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