Evidence map›Paper›PMID 31373216›Full record

ArticleAIDS research and human retroviruses

Current Challenges and Solutions in Research and Clinical Care of Older Persons Living with HIV: Findings Presented at the 9th International Workshop on HIV and Aging.

Erin E Sundermann, Kristine M Erlandson, Caitlin N Pope, Anna Rubtsova, Jessica Montoya, Alison A Moore, Catia Marzolini, Kelly K O'Brien, Savita Pahwa, Brendan A I Payne and 7 more

Abstract read
In one paragraph

Article in AIDS research and human retroviruses. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Challenges to Physical Activity Participation Among Older People Living with HIV: Scoping Review.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Erin E SundermannDepartment of Psychiatry, University of California, San Diego, La Jolla, California.
Kristine M ErlandsonDepartment of Medicine, University of Colorado-Anschutz Medical Center, Aurora, Colorado.
Caitlin N PopeAbigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio.
Anna RubtsovaDepartment of Behavioral Sciences and Health Education, Emory University Rollins School of Public Health, Atlanta, Georgia.
Jessica MontoyaDepartment of Psychiatry, University of California, San Diego, La Jolla, California.
Alison A MooreDivision of Geriatrics and Gerontology, Department of Medicine, University of California, San Diego, La Jolla, California.
Catia MarzoliniDivision of Infectious Diseases and Hospital Epidemiology, Departments of Medicine and Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland.
Kelly K O'BrienDepartment of Physical Therapy, University of Toronto, Toronto, Ontario, Canada.
Savita PahwaDepartment of Microbiology and Immunology and the Miami CFAR, University of Miami Miller School of Medicine, Miami, Florida.
Brendan A I PayneWellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, United Kingdom.
Leah H RubinDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Sharon WalmsleyToronto General Hospital, University Health Network, Toronto, Canada.
Norman J HaugheyDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Monty MontanoDepartment of Medicine, Harvard Medical School, Boston, Massachusetts.
Maile Y KarrisDivision of Infectious Diseases and Global Public Health, Department of Medicine, Unviersity of California San Diego, San Diego, California.
Joseph B MargolickDepartment of Molecular Microbiology and Immunology, Environmental Health and Engineering, and Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
David J MooreDepartment of Psychiatry, University of California, San Diego, La Jolla, California.

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4M
UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI David Mitchell Smith · 1994 to 2026
$78.4M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Multicenter Aids Cohort Study- Part B (Baltimore Site)U01AI035042 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BROWN, TODD T, MARGOLICK, JOSEPH B. · 1993 to 2018
$61.5M
STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello · 2001 to 2026
$50.4M
Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS) - Baltimore/Wash DC Center - Admin Supplement: Vision and dual sensory loss in HIV-infected older adultsU01HL146201 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI TODD T BROWN, Joseph B. Margolick · 2019 to 2026
$33.7M
Therapeutic CoreP30MH075673 · NIMH · JOHNS HOPKINS UNIVERSITY · PI Barbara Stauch Slusher · 2006 to 2026
$33.2M
California NeuroAIDS Tissue NetworkU24MH100928 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ACHIM, CRISTIAN L, MOORE, DAVID J · 2013 to 2023
$13.9M
San Diego Resource Center for advancing Alzheimer's Research in Minority Seniors (ARMS)P30AG059299 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOHN P. ELDER, PAUL E GILBERT · 2018 to 2026
$7.4M
Multi-Dimensional Successful Aging Among HIV-Infected AdultsR01MH099987 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JESTE, DILIP V., MOORE, DAVID J · 2013 to 2019
$3.8M
Biomarkers for Muscle Function and Aging in Chronic HIV InfectionR01AI108541 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MONTANO, MONTY A · 2014 to 2018
$3.7M
NCATS NIH HHS UL1 TR001442NHLBI NIH HHS U01 HL146201NIAAA NIH HHS K24 AA015957NIAID NIH HHS P30 AI036214NIAID NIH HHS P30 AI050409NIAID NIH HHS P30 AI060354NIAID NIH HHS R01 AI108541NIAID NIH HHS U01 AI035042NIA NIH HHS K23 AG050260NIA NIH HHS P30 AG059299NIA NIH HHS R01 AG054366NIA NIH HHS R21 AG055415NIMH NIH HHS P30 MH062512NIMH NIH HHS P30 MH075673NIMH NIH HHS R01 MH099987NIMH NIH HHS R25 MH080661NIMH NIH HHS R25 MH108389NIMH NIH HHS U24 MH100928
6 · The paper itself

Abstract

In the era of effective antiretroviral therapy, the number of older people with HIV (PWH) is increasing, and those aging with HIV are experiencing an increasing burden of age-associated comorbidities. Life expectancy among older PWH is approaching that of demographically comparable HIV-uninfected (HIV-) adults. With this changing demographic of PWH come new challenges for researchers and clinicians in how to identify, address, and manage the complex interplay of treated HIV infection and aging-associated factors. In response to these challenges, the annual International Workshop on HIV and Aging was initiated in 2009 as a multidisciplinary platform for scientific discourse on the research and clinical complications arising from the aging population of PWH. The multidisciplinary nature of the workshop has resulted in a wide range of topics addressed over the past 9 years, from basic mechanisms in aging and HIV pathogenesis, to epidemiology of aging within large cohorts, interventions, and implementation of clinical programs. Herein, we summarize the key topics discussed at the 9th Annual International Workshop on HIV and Aging 2018, including "inflammaging," mitochondrial dysfunction, exercise interventions, HIV-associated neurocognitive impairment, metabolic dysfunction, menopause, and polypharmacy. In addition to recent developments in research and clinical care, we discuss open questions and future research directions required to better understand the interaction of HIV and aging.

Indexed as

AgingDisease ManagementAgedAged, 80 and overComorbidityCongresses as TopicFemaleHIV InfectionsHumansInflammationLife ExpectancyMaleMenopauseResearchagingcomorbiditiesHIVinflammationinterventionpolypharmacy

Identifiers

PMID31373216
PMCPMC6862962

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.