Evidence map›Paper›PMID 31372873›Full record

ArticleObesity surgery2020

Laparoscopic Sleeve Gastrectomy on the Horizon as a Promising Treatment Modality for NAFLD.

Mohamed Abdalla Salman, Ahmed Abdallah Salman, Ahmed Abdelsalam, Mohamed Atallah, Hossam El-Din Shaaban, Ahmed El-Mikkawy, Mahmoud Gouda Omar, Mai Elshenoufy

Abstract read
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In one paragraph

Article in Obesity surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Review
  8. Comparative effectiveness of medical treatmentHepatobiliary surgery and nutrition · 2022
    Review
  9. Article
  10. Article
  11. Bariatric surgery, obesity and liver transplantation.Translational gastroenterology and hepatology · 2022
    Review
  12. Review
  13. Article
  14. Recent advances in the mechanisms underlying the beneficial effects of bariatric and metabolic surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2021
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mohamed Abdalla SalmanGeneral Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Ahmed Abdallah SalmanInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, 11311, Egypt. awea844@gmail.com.ORCID 0000-0003-0026-0841
Ahmed AbdelsalamGeneral Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Mohamed AtallahNational Hepatology and Tropical Medicine Research Institute, Cairo, Egypt.
Hossam El-Din ShaabanNational Hepatology and Tropical Medicine Research Institute, Cairo, Egypt.
Ahmed El-MikkawyHepatology and Gastroenterology Department, Theodor Bilharz Research Institute, Gizah, Egypt.
Mahmoud Gouda OmarInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, 11311, Egypt.
Mai ElshenoufyInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, 11311, Egypt.
Cairo University · EGNational Water Research Center · EGTheodor Bilharz Research Institute · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNonalcoholic fatty liver disease (NAFLD) is viewed as the hepatic manifestation of the metabolic syndrome with hepatic fatty infiltration is the common liver pathology. NAFLD can lead to nonalcoholic steatohepatitis (NASH), liver cirrhosis, liver cell failure, and liver malignancy.The present work aims to prospectively study the histological changes that occur in NAFLD obese patients 1-year post-laparoscopic sleeve gastrectomy (LSG) based on standardized NAS (NAFLD activity score). PATIENTS: This prospective study included 94 obese patients who underwent laparoscopic sleeve gastrectomy. Intraoperative wedge liver biopsy was taken from all patients with a follow-up liver biopsy at 12 months after the operation.

resultsLSG produced a marked reduction in body weight with a mean reduction in BMI from 44.54 + 5.45 to 34.23 + 2.66 kg/m

conclusionOur relatively large patient cohort shows a significant improvement of steatosis, steatohepatitis, and fibrosis at a 1-year follow-up. LSG can lead to resolution of NAFLD, and it may be in the near future another routine indication for bariatric surgery.

Indexed as

AdultBiopsyCohort StudiesFemaleFollow-Up StudiesGastrectomyHumansLaparoscopyLiverMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseObesityPrognosisProspective StudiesTreatment OutcomeLaparoscopic sleeve gastrectomyNAFLD

Identifiers

PMID31372873
OpenAlexW2965647492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.