ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020
Value of computerized shunt infusion study in assessment of pediatric hydrocephalus shunt function-a two center cross-sectional study.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 12 citations in OpenAlex.
- Review of the lumbar infusion test use in pediatric populations: state-of-the-art and future perspectives.Fluids and barriers of the CNS · 2025Review
- A Male Patient with Hydrocephalus via Multimodality Diagnostic Approaches: A Case Report.Cyborg and bionic systems (Washington, D.C.) · 2024Article
- Article
- In vitro testing of explanted shunt valves in hydrocephalic patients with suspected valve malfunction.Neurosurgical review · 2022Article
- Ventriculomegaly in children: nocturnal ICP dynamics identify pressure-compensated but active paediatric hydrocephalus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- CSF Dynamics for Shunt Prognostication and Revision in Normal Pressure Hydrocephalus.Journal of clinical medicine · 2021Review
- Shunt infusion studies: impact on patient outcome, including health economics.Acta neurochirurgica · 2020Article
- Slit ventricle syndrome: Historical considerations, diagnosis, pathophysiology, and treatment review.Brain circulationReview
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9 authors at 3 institutions in 4 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHydrocephalus shunt malfunction can-also in children-occur insidiously without clear symptoms of raised intracranial pressure (ICP) or changes in ventricular size, imposing a diagnostic challenge. Computerized shunt infusion studies enable quantitative shunt function assessment. We report on feasibility and results of this technique in children in a two center cross-sectional study. MATERIAL AND
methodsShunt infusion study (SIS) is performed with two needles inserted into a pre-chamber for ICP recording and CSF infusion. After baseline ICP recording, constant rate infusion is started until a new ICP plateau (ICPpl) is reached. Dedicated software containing the shunt's resistance characteristics calculates ICP and its amplitude outflow resistance and critical shunt pressure (CSP). Overall, 203 SIS were performed in 166 children. Shunts were defined as functional if ICPpl was <CSP and obstructed if ICPpl was > 5 mmHg above CSP and borderline in between.
resultsForty-one shunts (20.2%) were found obstructed, 26 (12.8%) had borderline characteristics, and 136 (67%) were functional. Baseline ICP in obstructed shunts was significantly above shunt operating pressure. CSF outflow resistance (R
conclusionSIS is a feasible, reliable, and radiation-free technique for quantitative shunt assessment to rule out or prove shunt malfunction. Dedicated software containing shunt hydrodynamic characteristics is necessary and small children may need short-term sedation. Due to the clinical and inherent economic advantages, SIS should be more frequently used in pediatric neurosurgery.
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