Evidence map›Paper›PMID 31372716›Full record

ArticleMolecular genetics and genomics : MGG2019

Insights into matrilineal genetic structure, differentiation and ancestry of Armenians based on complete mitogenome data.

Miroslava Derenko, Galina Denisova, Boris Malyarchuk, Anahit Hovhannisyan, Zaruhi Khachatryan, Peter Hrechdakian, Andrey Litvinov, Levon Yepiskoposyan

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular genetics and genomics : MGG, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Mitogenomics of modern Mongolic-speaking populations.Molecular genetics and genomics : MGG · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miroslava DerenkoGenetics Laboratory, Russian Academy of Sciences, Institute of Biological Problems of the North, Portovaya street, 18, 685000, Magadan, Russia. mderenko@mail.ru.ORCID http://orcid.org/0000-0002-1849-784X
Galina DenisovaGenetics Laboratory, Russian Academy of Sciences, Institute of Biological Problems of the North, Portovaya street, 18, 685000, Magadan, Russia.
Boris MalyarchukGenetics Laboratory, Russian Academy of Sciences, Institute of Biological Problems of the North, Portovaya street, 18, 685000, Magadan, Russia.
Anahit HovhannisyanRussian-Armenian University, Hovsep Emin Street, 123, 0051, Yerevan, Armenia.
Zaruhi KhachatryanInstitute of Molecular Biology, National Academy of Sciences, Hasratyan Street, 7, 0014, Yerevan, Armenia.
Peter HrechdakianArmenian DNA Project at Family Tree DNA, Houston, TX, 77008, USA.
Andrey LitvinovGenetics Laboratory, Russian Academy of Sciences, Institute of Biological Problems of the North, Portovaya street, 18, 685000, Magadan, Russia.
Levon YepiskoposyanRussian-Armenian University, Hovsep Emin Street, 123, 0051, Yerevan, Armenia.

Funding

Armenian National Science and Education Fund hubio-4562State Committee of Science 18T-1F186State Committee of Science NT-18/TBthe Ministry of Science and Higher Education of Russia The state assignment theme for the IBPN FEB RAS (0290-2018-0024)
6 · The paper itself

Abstract

Distinctive peculiarities of Armenians such as their millennia-long genetic isolation and strong national identity attract a keen interest while studying the demographic history of the West Asia. Here, to examine their fine-scale matrilineal genetic structure, ancestry and relationships with neighboring populations, we analyzed 536 complete mitogenomes (141 of which are novel) from 8 geographically different Armenian populations, covering the whole stretch of historical Armenia. The observed patterns highlight a remarkable degree of matrilineal genetic heterogeneity and weak population structuring of Armenians. Moreover, our phylogeographic analysis reveals common ancestries for some mtDNA lineages shared by West Asians, Transcaucasians, Europeans, Central Asians and Armenians. About third of the mtDNA subhaplogroups found in Armenian gene pool might be considered as Armenian-specific, as these are virtually absent elsewhere in Europe, West Asia and Transcaucasia. Coalescence ages of most of these lineages do not exceed 3.1 kya and coincide well with the population size growth started around 1.8-2.8 kya detectable only in the Bayesian Skyline Plots based on the Armenian-specific mtDNA haplotypes.

Indexed as

Genome, MitochondrialArmeniaAsia, CentralAsia, WesternDNA, MitochondrialEuropeGenetic VariationHaplotypesHumansPhylogenyPhylogeographyDNA, MitochondrialArmeniansGenetic differentiationGenetic diversityHaplogroupsMitochondrial DNA phylogenyMitochondrial genomes

Identifiers

PMID31372716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.