ArticlePain reports
Opportunities and challenges for junior investigators conducting pain clinical trials.
Article in Pain reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Starting Up Clinical Trials in Emergency Medicine: Advice and Acronyms for New Investigators.Journal of the American College of Emergency Physicians open · 2026Article
- Funding model for embedded research: Impacts, challenges, and lessons learned for investigators.Learning health systems · 2025Article
- Leveling the Playing Field for Mentors and Mentees in Academic Pain Medicine for the Benefit of Patients.Journal of pain research · 2024Article
- Challenges and opportunities for research clinicians interested in pain: results of a survey.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- The ACTTION Guide to Clinical Trials of Pain Treatments: standing on the shoulders of giants.Pain reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
introductionClinical investigation serves a vital role to advance treatment and management stratgies for patients with pain. For those new to clinical investigation, key advice for both the novice clinical-investigator and the experienced researcher expanding to translational work may accelerate research efforts.
objectiveTo review foundational material relevant to junior investigators focusing on pain clinical trials, with an emphasis on randomized controlled trials.
methodsWe reviewed recent publications and resources relevant to clinical investigators, with a particular emphasis on pain research.
resultsUnderstanding the approaches and barriers to clinical pain research is a first step to building a successful investigative portfolio. Key components of professional development include motivation, mentorship, and collaborative approaches to research. Many junior clinical-investigators face challenges in pursing research careers and sparking iterative progress towards success in clinical trials. Pain-specific research metrics and goals-including hypothesis development, study design considerations, and regulatory concerns-are also important considerations to junior investigators who pursue clinical trails. Approaches to build toward collaborative and independent funding are essential for investigators.
conclusionsThis work provides a foundation for understanding the clinical research process and helps inform the goals and plans of clinical-investigators.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.