Evidence map›Paper›PMID 31372513›Full record

ArticleCommunications biology2019

Ability of prebiotic polysaccharides to activate a HIF1α-antimicrobial peptide axis determines liver injury risk in zebrafish.

Zhen Zhang, Chao Ran, Qian-Wen Ding, Hong-Liang Liu, Ming-Xu Xie, Ya-Lin Yang, Ya-Dong Xie, Chen-Chen Gao, Hong-Ling Zhang, Zhi-Gang Zhou

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 115 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. iMeta · 2024
    Article
  9. Effects ofFrontiers in immunology · 2024
    Article
  10. Article
  11. Effects of the Exopolysaccharide fromFoods (Basel, Switzerland) · 2023
    Article
  12. The role of hypoxia-inducible factor 1α in hepatic lipid metabolism.Journal of molecular medicine (Berlin, Germany) · 2023
    Review
  13. Frontiers in nutrition · 2023
    Article
  14. Article
  15. Exopolysaccharide is the potential effector ofFrontiers in microbiology · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Excess DHA Induces Liver InjuryFrontiers in nutrition · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zhen Zhang *1China-Norway Joint Lab on Fish Gut Microbiota, Feed Research Institute, Chinese Academy of Agricultural Sciences, 100081 Beijing, China.
Chao Ran *2Key Laboratory of Feed Biotechnology, Ministry of Agriculture and Rural Affairs, Feed Research Institute, Chinese Academy of Agricultural Sciences, 100081 Beijing, China.
Qian-Wen Ding1China-Norway Joint Lab on Fish Gut Microbiota, Feed Research Institute, Chinese Academy of Agricultural Sciences, 100081 Beijing, China.
Hong-Liang Liu1China-Norway Joint Lab on Fish Gut Microbiota, Feed Research Institute, Chinese Academy of Agricultural Sciences, 100081 Beijing, China.
Ming-Xu Xie1China-Norway Joint Lab on Fish Gut Microbiota, Feed Research Institute, Chinese Academy of Agricultural Sciences, 100081 Beijing, China.
Ya-Lin Yang2Key Laboratory of Feed Biotechnology, Ministry of Agriculture and Rural Affairs, Feed Research Institute, Chinese Academy of Agricultural Sciences, 100081 Beijing, China.
Ya-Dong Xie1China-Norway Joint Lab on Fish Gut Microbiota, Feed Research Institute, Chinese Academy of Agricultural Sciences, 100081 Beijing, China.
Chen-Chen Gao1China-Norway Joint Lab on Fish Gut Microbiota, Feed Research Institute, Chinese Academy of Agricultural Sciences, 100081 Beijing, China.
Hong-Ling Zhang1China-Norway Joint Lab on Fish Gut Microbiota, Feed Research Institute, Chinese Academy of Agricultural Sciences, 100081 Beijing, China.
Zhi-Gang Zhou1China-Norway Joint Lab on Fish Gut Microbiota, Feed Research Institute, Chinese Academy of Agricultural Sciences, 100081 Beijing, China.
Chinese Academy of Agricultural Sciences · CNFeed Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural polysaccharides have received much attention for their ability to ameliorate hepatic steatosis induced by high-fat diet. However, the potential risks of their use have been less investigated. Here, we show that the exopolysaccharides (EPS) from

Indexed as

AnimalsAntimicrobial Cationic PeptidesDiet, High-FatFatty LiverGastrointestinal MicrobiomeHypoxia-Inducible Factor 1, alpha SubunitLactobacillusLarvaPolysaccharidesPrebioticsZebrafishAntimicrobial Cationic PeptidesHypoxia-Inducible Factor 1, alpha SubunitPolysaccharidesPrebioticsAntimicrobialsDysbiosisMicrobiotaNon-alcoholic fatty liver disease

Identifiers

PMID31372513
PMCPMC6658494
OpenAlexW2963549195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.