Evidence map›Paper›PMID 31372353›Full record

ArticleMethodsX2019

Stereotaxic surgery for implantation of guide cannulas for microinjection into the dorsomedial hypothalamus in young rats.

Emily I Poole, Jacob J McGavin, Nicholas L Cochkanoff, Karen M Crosby

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MethodsX, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emily I PooleBiology Department, Mount Allison University, 63B York Street, Sackville, New Brunswick, E4L 1G7, Canada.
Jacob J McGavinBiology Department, Mount Allison University, 63B York Street, Sackville, New Brunswick, E4L 1G7, Canada.
Nicholas L CochkanoffBiology Department, Mount Allison University, 63B York Street, Sackville, New Brunswick, E4L 1G7, Canada.
Karen M CrosbyBiology Department, Mount Allison University, 63B York Street, Sackville, New Brunswick, E4L 1G7, Canada.
Mount Allison University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stereotaxic surgery to implant guide cannulas into the rodent brain is a frequently used technique to deliver drugs to targeted brain regions in awake, freely moving animals. There are limited reports, however, of central injections in young animals, and no information on cannula implantation for drug administration into the dorsomedial hypothalamus (DMH) in young rats. Our protocol describes a simple and successful method for implanting guide cannulas in the brains of young, male Sprague-Dawley rats and outlines newly developed stereotaxic coordinates to accurately target the dorsomedial hypothalamus. •Stereotaxic surgical procedure for guide cannula implantation in the DMH in young rats.•Development of stereotaxic coordinates of the DMH in young rats.•Microinjection of drugs into the young rat brain.

Indexed as

Dorsomedial hypothalamic nucleusStereotaxic implantation of cannulas in the hypothalamus in young ratsStereotaxic surgeryYoung rats

Identifiers

PMID31372353
PMCPMC6660514
OpenAlexW2962256421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.