ArticleJournal of thoracic disease2019
Primary mediastinal neoplasms: a report of 1,005 cases from a single institution.
Article in Journal of thoracic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 25 citations in OpenAlex.
- Classification of mediastinal compartments: is separation of the superior mediastinum crucial?-a clinical practice review.Mediastinum (Hong Kong, China) · 2026Review
- Micronodular thymic epithelial tumors with lymphoid hyperplasia and mimicking lesions.Histology and histopathology · 2025Review
- Pediatric mediastinal lymphatic malformation: misdiagnosis analysis and literature review.BMC pediatrics · 2024Review
- Histopathological features of giant mediastinal tumors-a literature review.Mediastinum (Hong Kong, China) · 2023Review
- Retrospective analysis of the clinical presentation and imaging of eight primary benign mediastinal schwannomas.BMC research notes · 2021Article
- Sarcomas of the mediastinum with epithelioid morphology.Mediastinum (Hong Kong, China) · 2021Review
- An operated case of locally advanced thymic atypical carcinoid in anterior mediastinum: a case report.Translational cancer research · 2020Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study was an epidemiological analysis of all primary mediastinal neoplasms (PMNs) diagnosed between 2000 and 2016 at the National Tuberculosis and Lung Diseases Research Institute, Poland.
methodsAll patients with any mediastinal abnormality were included in the analysis. The patients' age and gender were obtained from the institutional database.
resultsFrom a cohort of 5,108 patients, 3,691 primary mediastinal lesions were found, including 1,005 (19%) PMNs: lymphomas (533, 53% of PMNs), thymomas (215, 21%), neurogenic tumors (NTs) (100, 10%), germ cell tumors (GCTs) (62, 6%), soft tissue tumors (STTs) (47, 5%) and thymic carcinomas/thymic neuroendocrine tumors (TCs/TNETs) (37 in total, 4%). The most frequent lymphomas were classical Hodgkin lymphomas [256] and primary mediastinal large B-cell lymphomas [163]. Type AB [73] predominated in thymomas and squamous cell carcinomas [9] and carcinoids [10] in TCs/TNETs. NTs encompassed mainly schwannomas [49], ganglioneuromas [21] and neurofibromas [10]. The most frequent STTs were hemangiomas [13] and lymphangiomas [11]. Lymphomas, thymomas and NT were more often in women, TCs/TNETs in men (P<0.001). Lymphomas predominated between the 2
conclusionsPMNs are rare conditions thus awareness of basic epidemiology may be very helpful for final diagnosis.
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