Evidence map›Paper›PMID 31372274›Full record

ArticleJournal of thoracic disease2019

Single-dose del Nido cardioplegia used in adult minimally invasive valve surgery.

Haiyan Luo, Xiaomin Qi, Hui Shi, Hui Zhao, Chaoqi Liu, Hongsong Chen, Runsheng Peng, Zhangsheng Yu, Kejian Hu, Chunsheng Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Del Nido versus Bretschneider HTK cardioplegia in adult aortic valve replacement: early clinical outcomes from a randomised trial.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
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  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haiyan LuoDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Xiaomin QiDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Hui ShiDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Hui ZhaoDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Chaoqi LiuDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Hongsong ChenDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Runsheng PengDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Zhangsheng YuDepartment of Bioinformatics and Biostatistics, SJTU-Yale Joint Center for Biostatistics, Jiao Tong University, Shanghai 200240, China.
Kejian HuDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Chunsheng WangDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Xin LiDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo analyze the protective effect of single-dose del Nido cardioplegia (DNC) in adult minimally invasive valve surgery.

methodsFrom January to December 2017, 165 consecutive adult patients who underwent minimally invasive valve surgery by the same team of surgeons were divided into two cohorts based on the type of cardioplegia administered during surgery: (I) single-dose DNC (DNC group (n=76, male 41, female 35) used in patients from May to December, 2017 and (II) intermittent standard 4:1 blood cardioplegia based on St.Thomas solution (SBC group, n=89, male 45, female 44) used in patients from January to April, 2017. Preoperative baseline demographics, preoperative comorbidities, operative variables, postoperative complications, and patient outcomes were collected and compared between the two groups.

resultsPreoperative characteristics were shown to be similar between the two groups before and after propensity matching. Patients in the DNC group required a significantly lower volume of cardioplegia. The volume of ultrafiltration in the DNC group was substantially higher than that in the SBC group. The spontaneous return of heartbeat rate in the DNC group was considerably higher than that in the SBC group (97.0%

conclusionsIn our initial experience, single-dose DNC in adult minimally invasive valve surgery in which the cross-clamp time was mostly less than 90 min, achieved equivalent myocardial protection and clinical outcomes when compared with standard whole blood cardioplegia. In addition, single-dose DNC made the minimally invasive valve surgery procedure progress in a smoother and more convenient fashion.

Indexed as

adult cardiac valve surgerydel Nido cardioplegia (DNC)Myocardial protection

Identifiers

PMID31372274
PMCPMC6626819

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.