Evidence map›Paper›PMID 31372264›Full record

ArticleJournal of thoracic disease2019

HIV-infected patients with opportunistic pulmonary infections misdiagnosed as lung cancers: the clinicoradiologic features and initial application of CT radiomics.

Weiya Shi, Lingxiao Zhou, Xueqing Peng, He Ren, Qinglei Wang, Fei Shan, Zhiyong Zhang, Lei Liu, Yuxin Shi

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  14. The increased recurrence rate of liver abscess caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Weiya ShiDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Lingxiao ZhouInstitutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Xueqing PengInstitutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
He RenInstitutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Qinglei WangDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Fei ShanDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Zhiyong ZhangDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Lei LiuInstitutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Yuxin ShiDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo characterize clinicoradiologic and radiomic features for identifying opportunistic pulmonary infections (OPIs) misdiagnosed as lung cancers in patients with human immunodeficiency virus (HIV).

methodsTwenty-four HIV-infected patients who were misdiagnosed with lung cancers on CT images and had OPIs confirmed by pathological examination or integration of clinical and laboratory findings and 49 HIV-infected patients with lung cancers confirmed pathologically were included. Semiautomated segmentation of the lesion was implemented with an in-house software. The lesion boundary was adjusted manually by radiologists. A total of 99 nonenhanced-CT-based radiomic features were then extracted with PyRadiomics. The clinicoradiologic and radiomic features were compared between the OPI and cancer groups.

resultsIn the OPI group, 19 patients (79.2%) had tuberculosis (TB) infections, 2 (8.3%) had nontuberculosis mycobacterium (NTM) infections, 2 (8.3%) had cryptococcus infections and 1 (4.2%) had a mixed infection of TB and NTM. There were significant differences in age, proportion of smokers, smoking index, highly active antiretroviral therapy (HAART) duration, CD4

conclusionsClinicoradiologic features together with radiomics may help identify OPIs mimicking lung cancers in HIV-infected patients.

Indexed as

Human immunodeficiency virus (HIV)lung canceropportunistic pulmonary infection (OPI)radiomicsX-ray computed tomography

Identifiers

PMID31372264
PMCPMC6626777

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.