ArticleJournal of materials chemistry. B2019
Electrospinning of Highly Aligned Fibers for Drug Delivery Applications.
Article in Journal of materials chemistry. B, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Enrichment of colon cancer stem cells via polymeric porous filters with different zeta potentials.Regenerative biomaterials · 2026Article
- A process optimization and release modeling of coaxial electrospun aligned core-shell poly (ethylene oxide-poly(l-lactide-co-glycolide)) nanofibers encapsulating nerve growth factor.Journal of applied polymer science · 2025Article
- Integrating synthetic polypeptides with innovative material forming techniques for advanced biomedical applications.Journal of nanobiotechnology · 2025Review
- Electrospun nanofibers: Focus on local therapeutic delivery targeting infectious disease.Journal of drug delivery science and technology · 2025Article
- Electrospun nanofibers and their application as sensors for healthcare.Frontiers in bioengineering and biotechnology · 2025Review
- Evaluating the efficacy of uniformly designed square mesh resin 3D printed scaffolds in directing the orientation of electrospun PCL nanofibers.Scientific reports · 2024Article
- Advances in Electrospun Nanofiber Membranes for Dermatological Applications: A Review.Molecules (Basel, Switzerland) · 2024Review
- Development of Polyvinyl Alcohol (PVA) Nanofibers Containing Cationic Lipid/siRNA Complexes via Electrospinning: The Impact of PVA Characterization.Nanomaterials (Basel, Switzerland) · 2024Article
- Pressure-Spun Fibrous Surgical Sutures for Localized Antibacterial Delivery: Development, Characterization, and In Vitro Evaluation.ACS applied materials & interfaces · 2023Article
- Extracellular Matrix-Based and Electrospun Scaffolding Systems for Vaginal Reconstruction.Bioengineering (Basel, Switzerland) · 2023Review
- Gelatin methacryloyl hydrogel as an injectable scaffold with multi-therapeutic effects to promote antimicrobial disinfection and angiogenesis for regenerative endodontics.Journal of materials chemistry. B · 2023Article
- Topographic Orientation of Scaffolds for Tissue Regeneration: Recent Advances in Biomaterial Design and Applications.Biomimetics (Basel, Switzerland) · 2022Review
- Prospects and Challenges of Electrospun Cell and Drug Delivery Vehicles to Correct Urethral Stricture.International journal of molecular sciences · 2022Review
- Electrospun Materials for Biomedical Applications.Pharmaceutics · 2022Article
- Purification of Colon Carcinoma Cells from Primary Colon Tumor Using a Filtration Method via Porous Polymeric Filters.Polymers · 2021Article
- Novel Poly(ester urethane urea)/Polydioxanone Blends: Electrospun Fibrous Meshes and Films.Molecules (Basel, Switzerland) · 2021Article
- Fabrication of Nano/Micro-Structured Electrospun Detection Card for the Detection of Pesticide Residues.Foods (Basel, Switzerland) · 2021Article
- Article
- Development of an antibacterial and anti-metalloproteinase dental adhesive for long-lasting resin composite restorations.Journal of materials chemistry. B · 2020Article
- Topographical and Biomechanical Guidance of Electrospun Fibers for Biomedical Applications.Polymers · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Electrospinning is a straightforward, cost-effective, and versatile technique for fabrication of polymeric micro/nanofibers with tunable structural properties. Controlling the size, shape, and spatial orientation of the electrospun fibers is crucial for utilization in drug delivery and tissue engineering applications. In this study, for the first time, we systematically investigate the effect of processing parameters, including voltage, syringe needle gauge, angular velocity of rotating wheel, syringe-collector distance, and flow rate on the size and alignment of electrospun PLGA fibers. Optimizing these parameters enabled us to produce highly aligned and monodisperse PLGA fibers (spatial orientation> 99% and coefficient of variation< 0.5). To assess the effect of fiber alignment on the release of encapsulated drugs from these fibers, we incorporated dexamethasone, an anti-inflammatory drug, within highly-aligned and randomly-oriented fibers with comparable diameters (~0.87 μm) and compared their release profiles.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.