ArticlePakistan journal of medical sciences
Hypopituitarism other than sellar and parasellar tumors or traumatic brain injury assessed in a tertiary hospital.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Case series of unusual cases of hypothyroidism-induced pericardial effusion.Journal of family medicine and primary care · 2024Article
- Pituitary Apoplexy: An Updated Review.Journal of clinical medicine · 2024Review
- An unusual presentation of hypopituitarism caused by a sellar aneurysm.Archives of endocrinology and metabolism · 2024Article
- Recurrent Pericardial Effusion Due to Panhypopituitarism: A Rare Case Report.International journal of endocrinology and metabolism · 2023Article
- Sheehan syndrome: Cardiovascular and metabolic comorbidities.Frontiers in endocrinology · 2023Review
- Pericardial Effusion as an Initial Presentation of Panhypopituitarism.European journal of case reports in internal medicine · 2020Article
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Authors and funding
7 authors.
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Abstract
objectiveData regarding the etiology, clinical and biochemical patterns in hypopituitarism is scant for Pakistan. We describe the characteristics of patients with hypopituitarism other than sellar and parasellar tumors or traumatic brain injury from a tertiary care center in Pakistan.
methodsWe conducted a retrospective descriptive study in the Aga Khan University Hospital, Karachi, Pakistan. We studied all patients presenting with hypopituitarism, between January 2004 and December 2013. Clinical, hormonal and imaging data pertinent to the study was collected according to inclusion criteria.
resultsForty-two patients presented to the endocrinology clinics at the Aga Khan University Hospital during the study period. Thirty-seven patients (88.1%) were females. Mean age ± standard deviation of the participants was 53.8 ± 14.7 years. Sixteen patients had secondary infertility and all were females; a majority of patients in this group had Sheehan's syndrome (n=8) followed by empty sella syndrome (n=3), partial empty sella syndrome (n=2), idiopathic cause (n=2) and tuberculoma (n=1). Eighteen females (48.6%) reported inability to lactate.
conclusionsNon-traumatic hypopituitarism was more common in women, with Sheehan syndrome being the most common cause of hypopituitarism in our study (35.7%). Secondary hypothyroidism was the most common hormonal deficiency. The most commonly reported symptom was weakness.
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