Evidence map›Paper›PMID 31371952›Full record

SynthesisInternational journal of nanomedicine2019

Antiangiogenic properties of nanoparticles: a systematic review.

Brhaish Ali Saeed, Vuanghao Lim, Nor Adlin Yusof, Kang Zi Khor, Heshu Sulaiman Rahman, Nozlena Abdul Samad

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
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  5. Recent Cutting-Edge Technologies for the Delivery of Peptide Nucleic Acid.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brhaish Ali SaeedIntegrative Medicine Cluster, Advanced Medical and Dental Institute, SAINS@ Bertam, Universiti Sains Malaysia, Kepala Batas 13200, Pulau Pinang, Malaysia.
Vuanghao LimIntegrative Medicine Cluster, Advanced Medical and Dental Institute, SAINS@ Bertam, Universiti Sains Malaysia, Kepala Batas 13200, Pulau Pinang, Malaysia.
Nor Adlin YusofIntegrative Medicine Cluster, Advanced Medical and Dental Institute, SAINS@ Bertam, Universiti Sains Malaysia, Kepala Batas 13200, Pulau Pinang, Malaysia.
Kang Zi KhorIntegrative Medicine Cluster, Advanced Medical and Dental Institute, SAINS@ Bertam, Universiti Sains Malaysia, Kepala Batas 13200, Pulau Pinang, Malaysia.
Heshu Sulaiman RahmanDepartment of Clinic and Internal Medicine, College of Veterinary Medicine, University of Sulaimani, Sulaymaniyah City 46001, Republic of Iraq.
Nozlena Abdul SamadIntegrative Medicine Cluster, Advanced Medical and Dental Institute, SAINS@ Bertam, Universiti Sains Malaysia, Kepala Batas 13200, Pulau Pinang, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles appear to be one of the most promising agents that offer efficacy in angiogenesis-related disease therapy. The objective of this research is to systematically review studies that have probed into the effect of nanoparticles on angiogenesis. Selected inclusion criteria were used to extract articles, references that were cited in the initial search were sought to identify more potential articles, and articles that did not meet the inclusion criteria and duplicates were discarded. The spherical shape was shown to be the most common shape employed to investigate the role of nanoparticles in angiogenesis therapy. The size of nanoparticles appears to play a crucial role for efficacy on angiogenesis, in which 20 nm emerged as the preferred size. Gold nanoparticles exhibit the most promise as an antiangiogenesis agent, and the toxicity was adjustable based on the dosages applied.

Indexed as

Angiogenesis InhibitorsHumansNanoparticlesNeovascularization, PathologicParticle SizeAngiogenesis Inhibitorsangiogenesisantiangiogenesisnanoparticlesshapesizetoxicity

Identifiers

PMID31371952
PMCPMC6630093

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.