Evidence map›Paper›PMID 31371930›Full record

SynthesisClinical interventions in aging2019

Different durations of cognitive stimulation therapy for Alzheimer's disease: a systematic review and meta-analysis.

Juexuan Chen, Yuting Duan, Huanjie Li, Liming Lu, Jihong Liu, Chunzhi Tang

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. The evaluation of the Jigsawdio program on the cognitive and mental health of people living with dementia: Mixed methods study.Gerontechnology : international journal on the fundamental aspects of technology to serve the ageing society · 2025
    Article
  5. Review
  6. Article
  7. Global rural health disparities in Alzheimer's disease and related dementias: State of the science.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Diagnosis of Early Alzheimer's Disease: Clinical Practice in 2021.The journal of prevention of Alzheimer's disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Juexuan Chen *Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Yuting Duan *Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Huanjie LiFoshan Hospital of Traditional Chinese Medicine, Affiliated to Guangzhou University of Chinese Medicine, Foshan, People's Republic of China.
Liming LuMedical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Jihong LiuFoshan Hospital of Traditional Chinese Medicine, Affiliated to Guangzhou University of Chinese Medicine, Foshan, People's Republic of China.
Chunzhi TangMedical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy of cognitive stimulation therapy (CST) of different durations for Alzheimer's disease (AD).

methodsA comprehensive search was carried out in three databases. The primary outcome was Mini-Mental State Examination (MMSE) score. We conducted a meta-analysis with Review Manager, version 5.3 and assessed the methodological quality of the included studies using the Cochrane Collaboration Recommendations assessment tool.

resultsTreatment effects from the meta-analysis showed that CST plus acetylcholinesterase inhibitors (ChEIs) was better than the control assessed by MMSE. In addition, the meta-analysis indicated that long-term CST was better than short-term or maintenance CST.

conclusionOur study confirmed that the combination of CST and drug treatment for AD is effective in AD, regardless of whether short-term CST, maintenance CST, or long-term CST is used. The long-term CST appears to be more effective.

Indexed as

Alzheimer DiseaseCholinesterase InhibitorsCognition DisordersCognitive Behavioral TherapyHumansRandomized Controlled Trials as TopicSocial BehaviorCholinesterase InhibitorsAlzheimer’s diseasecognitive stimulation therapycognitive symptommeta-analysis

Identifiers

PMID31371930
PMCPMC6635834
OpenAlexW2959539167

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.