ArticleClinical ophthalmology (Auckland, N.Z.)2019
Optimal management of pediatric keratoconus: challenges and solutions.
Article in Clinical ophthalmology (Auckland, N.Z.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Early Detection of Keratoconus: Diagnostic Advances and Their Impact on Visual Outcomes: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Comparison of Efficacy and Safety Between Standard, Accelerated Epithelium-Off and Transepithelial Corneal Collagen Crosslinking in Pediatric Keratoconus: A Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Paediatric Keratoconus: An ERN-EYE Clinical Consensus Statement on Diagnosis, Treatment and Follow-Up Care.Ophthalmology and therapy · 2026Review
- Clinical and demographic profile of patients with keratoconus in the Eastern Cape, South Africa.Journal of the colleges of medicine of South Africa · 2026Article
- Progression and regression of keratoconus in an Iranian population.Scientific reports · 2025Article
- Tear Proteomic Analysis From Offspring of Keratoconus Patients: New Insights Into Corneal Biomechanical Weakness and Disease Risk Stages.Investigative ophthalmology & visual science · 2025Article
- Keratoconus in children in Tunisia: Epidemiological, clinical and therapeutic features.La Tunisie medicale · 2025Article
- Understanding Keratoconus in Down Syndrome: From Etiology to Management - A Narrative Review.Clinical ophthalmology (Auckland, N.Z.) · 2025Review
- Pediatric keratoconus epidemiology: a systematic scoping review.International ophthalmology · 2024Article
- Barriers to the Diagnosis and Management of Keratoconus Among Optometrists in Kenya.Clinical optometry · 2024Article
- Diagnosis and management of keratoconus in the paediatric age group: a review of current evidence.Eye (London, England) · 2023Review
- National survey of corneal cross-linking (CXL) practice patterns in the United Kingdom during 2019.Eye (London, England) · 2023Article
- Diagnostic accuracy of different keratoconus detection indices of pentacam in paediatric eyes.Eye (London, England) · 2023Article
- Three-year follow-up of accelerated versus standard corneal cross-linking in paediatric Keratoconus.Eye (London, England) · 2023Article
- Natural history and predictors for progression in pediatric keratoconus.Scientific reports · 2023Article
- Diagnosis and management of keratoconus by eye care practitioners in Kenya.BMC ophthalmology · 2023Article
- Independent-effect comparison of five crosslinking procedures for Progressive Keratoconus based on Keratometry and the ABCD Grading System using Generalized Estimating Equations (GEE).BMC ophthalmology · 2023Article
- Outcome indicators for cross linking in pediatric keratoconus.Frontiers in medicine · 2023Article
- Development and validation to predict visual acuity and keratometry two years after corneal crosslinking with progressive keratoconus by machine learning.Frontiers in medicine · 2023Article
- Investigating the role of inflammation in keratoconus: A retrospective analysis of 551 eyes.European journal of ophthalmology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Keratoconus (KC) shows several distinctive features in clinical appearance, disease progression, and treatment in children compared with adults. Therefore, diagnostic, clinical care, and therapeutic approaches are different. However, pediatric keratoconus is often undiagnosed and thus untreated in many cases. Once diagnosis has been made, compliance with treatment recommendations is often poor. Pediatric keratoconus also tends to have more rapid progression than in adults; therefore, early detection and treatment are paramount to prevent serious vision impairment, which can affect the child's development. This review of pediatric keratoconus discusses important issues such as worldwide epidemiology, clinical features in children compared to adults, and challenges in diagnosis and treatment and focuses on the most appropriate management strategies based on the best available current evidence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.