ArticleCell death and differentiation2020
Increasing Ca
Open access · hybridAbstract read
In one paragraph
Article in Cell death and differentiation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 34 citations in OpenAlex.
- Elevating levels of neuronal MCU in the hippocampus enhances mitochondrial calcium uptake and respiratory efficiency proportional to demand.bioRxiv : the preprint server for biology · 2026Article
- Dysfunction of α2δ4 leads to photoreceptor degeneration through disrupted synaptic mitochondria and calcium crosstalk.Cell death & disease · 2026Article
- Quantitative Proteomics Identifies Potential Molecular Adaptations in Mouse Models of Congenital Stationary Night Blindness Type 2.Molecular & cellular proteomics : MCP · 2025Article
- Retinopathy-associated inosine monophosphate dehydrogenase 1 mutations cause metabolic and filament defects in cones.Disease models & mechanisms · 2025Article
- Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx.Journal of advanced research · 2025Article
- MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology.Journal of advanced research · 2025Review
- Response Plasticity ofInternational journal of molecular sciences · 2024Article
- Coenzyme Q10 eyedrops conjugated with vitamin E TPGS alleviate neurodegeneration and mitochondrial dysfunction in the diabetic mouse retina.Frontiers in cellular neuroscience · 2024Article
- Layer-specific mitochondrial diversity across hippocampal CA2 dendrites.Hippocampus · 2023Article
- Mitochondria-related genes and metabolic profiles of innate and adaptive immune cells in primary Sjögren's syndrome.Frontiers in immunology · 2023Article
- Article
- Applying Protein-Protein Interactions and Complex Networks to Identify Novel Genes in Retinitis Pigmentosa Pathogenesis.International journal of molecular sciences · 2022Article
- Mitochondrial calcium exchange in physiology and disease.Physiological reviews · 2022Review
- A highly conserved zebrafish IMPDH retinal isoform produces the majority of guanine and forms dynamic protein filaments in photoreceptor cells.The Journal of biological chemistry · 2022Article
- MICU3 regulates mitochondrial CaCell death & disease · 2021Article
- An Analysis of Metabolic Changes in the Retina and Retinal Pigment Epithelium of Aging Mice.Investigative ophthalmology & visual science · 2021Article
- Retina Metabolism and Metabolism in the Pigmented Epithelium: A Busy Intersection.Annual review of vision science · 2021Review
- Metabolism in the Zebrafish Retina.Journal of developmental biology · 2021Review
- Photoreceptor metabolic reprogramming: current understanding and therapeutic implications.Communications biology · 2021Review
- Zebrafish Models of Photoreceptor Dysfunction and Degeneration.Biomolecules · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Rachel A HuttoBiochemistry Department, University of Washington, Seattle, WA, 98109, USA.ORCID http://orcid.org/0000-0003-2766-9719
Celia M BisbachBiochemistry Department, University of Washington, Seattle, WA, 98109, USA.
Fatima AbbasJohn A. Moran Eye Center, University of Utah, Salt Lake City, UT, 84132, USA.
Daniel C BrockBiochemistry Department, University of Washington, Seattle, WA, 98109, USA.
Whitney M CleghornBiochemistry Department, University of Washington, Seattle, WA, 98109, USA.
Edward D ParkerOpthalmology Department, University of Washington, Seattle, WA, 98109, USA.
Benjamin H BauerBiochemistry Department, University of Washington, Seattle, WA, 98109, USA.
William GeBiochemistry Department, University of Washington, Seattle, WA, 98109, USA.
Frans VinbergJohn A. Moran Eye Center, University of Utah, Salt Lake City, UT, 84132, USA.
James B HurleyBiochemistry Department, University of Washington, Seattle, WA, 98109, USA.
Susan E BrockerhoffBiochemistry Department, University of Washington, Seattle, WA, 98109, USA. sbrocker@uw.edu.
University of Washington · USUniversity of Utah · US
Funding
Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1986 to 2026
$41.4MVision Research CoreP30EY001730 · NEI · UNIVERSITY OF WASHINGTON · PI JAMES Bryant HURLEY · 1985 to 2026
$23.5MTRAINING IN MOLECULAR AND CELLULAR BIOLOGYT32GM007270 · NIGMS · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W · 1985 to 2020
$21.0MUniversity of Utah, Core Vision Research GrantP30EY014800 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Bryan William Jones · 2005 to 2026
$14.6MROD AND CONE RESPONSE CHARACTERISTICSR01EY006641 · NEI · UNIVERSITY OF WASHINGTON · PI JAMES Bryant HURLEY · 1986 to 2026
$10.2MTRAINING PROGRAM IN GENETICST32GM007464 · NIGMS · UNIVERSITY OF UTAH · PI GRUNWALD, DAVID J., STANFIELD, GILLIAN · 1985 to 2020
$6.1MPhotoreceptor Mitochondria and Ca2+ DynamicsR01EY026020 · NEI · UNIVERSITY OF WASHINGTON · PI BROCKERHOFF, SUSAN E, HURLEY, JAMES BRYANT · 2016 to 2024
$3.6MVision Research Training Grant at the University of UtahT32EY024234 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI DAVID KRIZAJ, Monica L Vetter · 2014 to 2026
$2.3MAssessment of Retinal Function in Health and Disease From Mouse To HumanR00EY026651 · NEI · UNIVERSITY OF UTAH · PI VINBERG, FRANS · 2017 to 2019
$722kExpansion of a Zebrafish Research Core FacilityG20OD018369 · OD · UNIVERSITY OF UTAH · PI GRUNWALD, DAVID J. · 2014 to 2014
$500kEnhancing Metabolic Features that Promote Photoreceptor SurvivalR21EY028645 · NEI · UNIVERSITY OF WASHINGTON · PI BROCKERHOFF, SUSAN E · 2018 to 2019
$440kUnderstanding the role of cytosolic NADH production in maintaining aerobic glycolysis in the retinaF31EY031165 · NEI · UNIVERSITY OF WASHINGTON · PI BISBACH, CELIA · 2020 to 2021
$76kNEI NIH HHS F31 EY031165NEI NIH HHS P30 EY001730NEI NIH HHS P30 EY014800NEI NIH HHS R00 EY026651NEI NIH HHS R01 EY006641NEI NIH HHS R01 EY026020NEI NIH HHS R21 EY028645NEI NIH HHS T32 EY024234NIDDK NIH HHS P30 DK017047NIGMS NIH HHS T32 GM007270NIGMS NIH HHS T32 GM007464NIH HHS G20 OD018369
Abstract
Photoreceptors are specialized neurons that rely on Ca
Indexed as
Adaptation, PhysiologicalLightMetabolomeStress, PhysiologicalAnimalsCalciumCalcium ChannelsCytosolDisease Models, AnimalIsocitrate DehydrogenaseKetoglutarate Dehydrogenase ComplexKineticsLight Signal TransductionMitochondriaModels, BiologicalPhenotypeCalciumCalcium ChannelsIsocitrate DehydrogenaseKetoglutarate Dehydrogenase Complexmitochondrial calcium uniporter
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.