ArticleProceedings of the National Academy of Sciences of the United States of America2019
Contrasting evolution of virulence and replication rate in an emerging bacterial pathogen.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Virulent Parasites Emerge in Hosts With Rising Temperatures.Global change biology · 2026Article
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- Host Disease Tolerance Predicts Transmission Probability for a Songbird Pathogen.Ecology and evolution · 2025Article
- Structure of Extracellular Vesicles and Their Effect on Bacterial Biofilms Change with the Development of Antibiotic Resistance in the Probiotic Strain Lactiplantibacillus plantarum 8p-a3.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2024Article
- Evolution of the CRISPR-Cas9 defence system inMicrobial genomics · 2024Article
- Incomplete immunity in a natural animal-microbiota interaction selects for higher pathogen virulence.Current biology : CB · 2024Article
- Metabolic efficiency reshapes the seminal relationship between pathogen growth rate and virulence.Ecology letters · 2023Article
- Parasite detection and quantification in avian blood is dependent on storage medium and duration.Ecology and evolution · 2023Article
- High virulence is associated with pathogen spreadability in a songbird-bacterial system.Royal Society open science · 2023Article
- Development of Resistance to Clarithromycin and Amoxicillin-Clavulanic Acid inMicrobiology spectrum · 2022Article
- Investigating Pathogenicity and Virulence ofInternational journal of molecular sciences · 2021Article
- Microbial evolution and transitions along the parasite-mutualist continuum.Nature reviews. Microbiology · 2021Review
- The three Ts of virulence evolution during zoonotic emergence.Proceedings. Biological sciences · 2021Review
- Host genotype and genetic diversity shape the evolution of a novel bacterial infection.The ISME journal · 2021Article
- Levels of pathogen virulence and host resistance both shape the antibody response to an emerging bacterial disease.Scientific reports · 2021Article
- Article
- Article
- Experimental evidence for stabilizing selection on virulence in a bacterial pathogen.Evolution letters · 2020Article
- Emerging pathogen evolution: Using evolutionary theory to understand the fate of novel infectious pathogens.EMBO reports · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Host resistance through immune clearance is predicted to favor pathogens that are able to transmit faster and are hence more virulent. Increasing pathogen virulence is, in turn, typically assumed to be mediated by increasing replication rates. However, experiments designed to test how pathogen virulence and replication rates evolve in response to increasing host resistance, as well as the relationship between the two, are rare and lacking for naturally evolving host-pathogen interactions. We inoculated 55 isolates of
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