Evidence map›Paper›PMID 31371451›Full record

ArticleThe Journal of biological chemistry2019

A molecular triage process mediated by RING finger protein 126 and BCL2-associated athanogene 6 regulates degradation of G

Kenta Kamikubo, Hisakazu Kato, Hidetaka Kioka, Satoru Yamazaki, Osamu Tsukamoto, Yuya Nishida, Yoshihiro Asano, Hiromi Imamura, Hiroyuki Kawahara, Yasunori Shintani and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Recent advances on the role of G0S2.Discover oncology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. A Novel Role for RNF126 in the Promotion of G2 Arrest via Interaction With 14-3-3σ.International journal of radiation oncology, biology, physics · 2022
    Article
  12. Article
  13. Article
  14. Protein Quality Control and Lipid Droplet Metabolism.Annual review of cell and developmental biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Kenta KamikuboDepartment of Medical Biochemistry, Osaka University Graduate School of Frontier Biosciences, Suita, Osaka 565-0871, Japan.
Hisakazu KatoDepartment of Medical Biochemistry, Osaka University Graduate School of Frontier Biosciences, Suita, Osaka 565-0871, Japan katohisa@medbio.med.osaka-u.ac.jp.
Hidetaka KiokaDepartment of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
Satoru YamazakiDepartment of Cell Biology, National Cerebral and Cardiovascular Center, Suita, Osaka 565-8565, Japan.
Osamu TsukamotoDepartment of Medical Biochemistry, Osaka University Graduate School of Frontier Biosciences, Suita, Osaka 565-0871, Japan.
Yuya NishidaDepartment of Medical Biochemistry, Osaka University Graduate School of Frontier Biosciences, Suita, Osaka 565-0871, Japan.ORCID 0000-0002-1994-0807
Yoshihiro AsanoDepartment of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
Hiromi ImamuraLaboratory of Functional Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.
Hiroyuki KawaharaLaboratory of Cell Biology and Biochemistry, Department of Biological Sciences, Tokyo Metropolitan University, Tokyo, 192-0397, Japan.
Yasunori ShintaniDepartment of Medical Biochemistry, Osaka University Graduate School of Frontier Biosciences, Suita, Osaka 565-0871, Japan.
Seiji TakashimaDepartment of Medical Biochemistry, Osaka University Graduate School of Frontier Biosciences, Suita, Osaka 565-0871, Japan takasima@cardiology.med.osaka-u.ac.jp.
The University of Osaka · JPJapan Science and Technology Agency · JPKyoto University · JPNational Cerebral and Cardiovascular Center · JPTokyo Metropolitan University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative phosphorylation generates most of the ATP in respiring cells. ATP is an essential energy source, especially in cardiomyocytes because of their continuous contraction and relaxation. Previously, we reported that G

Indexed as

Oxidative PhosphorylationAdenosine TriphosphateAlanineCell Cycle ProteinsGene Expression RegulationHeLa CellsHumansHydrophobic and Hydrophilic InteractionsMitochondriaMolecular ChaperonesMultiprotein ComplexesMutationMyocardial IschemiaMyocytes, CardiacProteolysisUbiquitinationAdenosine TriphosphateAlanineBAG6 protein, humanCell Cycle ProteinsG0S2 protein, humanMolecular ChaperonesMultiprotein ComplexesRNF126 protein, humanUbiquitin-Protein LigasesATPBCL2-associated athanogene 6hypoxiaischemic heart diseasemitochondriaprotein degradationRING finger protein 126 (RNF126)small interfering RNA (siRNA)ubiquitin ligase

Identifiers

PMID31371451
PMCPMC6779449
OpenAlexW2965005269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.