Evidence map›Paper›PMID 31371436›Full record

ArticleGenes & development2019

Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells.

Federico Comoglio, Marta Simonatto, Sara Polletti, Xin Liu, Stephen T Smale, Iros Barozzi, Gioacchino Natoli

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 40 citations in OpenAlex.

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  6. Examining NF-κB genomic interactions by ChIP-seq and CUT&Tag.bioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Federico Comoglio *Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands.
Marta Simonatto *Humanitas University (Hunimed), Pieve Emanuele, Milano 20090, Italy.
Sara PollettiHumanitas University (Hunimed), Pieve Emanuele, Milano 20090, Italy.
Xin LiuDepartment of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles (UCLA), Los Angeles, California 90095, USA.
Stephen T SmaleDepartment of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles (UCLA), Los Angeles, California 90095, USA.
Iros Barozzi *Department of Surgery and Cancer, Imperial College London, London W12 00N, United Kingdom.
Gioacchino Natoli *Humanitas University (Hunimed), Pieve Emanuele, Milano 20090, Italy.
Humanitas University · ITUniversity of California, Los Angeles · USImperial College London · GBOncode Institute · NL

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
European Research Council 692789NCI NIH HHS P30 CA016042
6 · The paper itself

Abstract

Accessibility of the genomic regulatory information is largely controlled by the nucleosome-organizing activity of transcription factors (TFs). While stimulus-induced TFs bind to genomic regions that are maintained accessible by lineage-determining TFs, they also increase accessibility of thousands of

Indexed as

AnimalsCells, CulturedChromatin ImmunoprecipitationHigh-Throughput Nucleotide SequencingMacrophagesMiceMice, Inbred C57BLMicrococcal NucleaseNucleosomesRegulatory Elements, TranscriptionalTranscription FactorsMicrococcal NucleaseNucleosomesTranscription Factorschromatinmacrophagesnucleosome

Identifiers

PMID31371436
PMCPMC6719622
OpenAlexW2965584346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.