Evidence map›Paper›PMID 31371434›Full record

Trial reportArchives of disease in childhood. Fetal and neonatal edition2020

Randomised trial of cord clamping at very preterm birth: outcomes at 2 years.

Lindsay Armstrong-Buisseret, Katie Powers, Jon Dorling, Lucy Bradshaw, Samantha Johnson, Eleanor Mitchell, Lelia Duley

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Archives of disease in childhood. Fetal and neonatal edition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Cord management in non-vigorous newborns.Seminars in perinatology · 2023
    Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Lindsay Armstrong-BuisseretNottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0000-0002-8045-5464
Katie PowersNottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK.
Jon DorlingDivision of Neonatal-Perinatal Medicine, Dalhousie University, Halifax, Canada.
Lucy BradshawNottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK.
Samantha JohnsonDepartment of Health Sciences, University of Leicester, Leicester, UK.
Eleanor MitchellNottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK.
Lelia DuleyNottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0000-0001-6721-5178

Funding

Department of Health RP-PG-0609-10107
6 · The paper itself

Abstract

objectiveTo report outcomes at 2 years corrected age for children of women recruited to a trial comparing alternative policies for timing of cord clamping and immediate neonatal care at very preterm birth.

designParallel group randomised (1:1) trial.

settingEight UK tertiary maternity units.

participantsTwo hundred and seventy-six babies born to 261 women expected to have a live birth before 32

interventionsDeferred cord clamping (≥2 min) and immediate neonatal care with cord intact or immediate (≤20 s) clamping and immediate neonatal care after clamping.

main outcome measureComposite of death or adverse neurodevelopmental outcome at 2 years corrected age.

resultsSix babies born after 35

conclusionsDeferred clamping and immediate neonatal care with cord intact may reduce the risk of death or adverse neurodevelopmental outcome at 2 years of age for children born very premature. Confirmation in larger studies is needed to determine the real benefits and harms. TRIAL REGISTRATION NUMBER: ISRCTN21456601.

Indexed as

Premature BirthUmbilical CordAdultChild DevelopmentChild, PreschoolFemaleHumansInfant, Extremely PrematureInfant, NewbornPilot ProjectsSingle-Blind MethodTime FactorsUnited Kingdomneonatal care with cord intactoutcomes at 2 years corrected age

Identifiers

PMID31371434
PMCPMC7363783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.