Evidence map›Paper›PMID 31371307›Full record

ArticleBiology open2019

MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis.

Haijiang Qiu, Fangchao Chen, Minjun Chen

Abstract read
In one paragraph

Article in Biology open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. The miRNAs Role in Melanoma and in Its Resistance to Therapy.International journal of molecular sciences · 2020
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Haijiang QiuDepartment of Rheumatology & Immunology, the Guangzhou First People's Hospital, the Second Affiliated Hospital of South China University of Technology, Guangzhou 510641, China haijqiu@126.com.ORCID http://orcid.org/0000-0002-3933-509X
Fangchao ChenDepartment of Rheumatology & Immunology, the Guangzhou First People's Hospital, the Second Affiliated Hospital of South China University of Technology, Guangzhou 510641, China.
Minjun ChenDepartment of Rheumatology & Immunology, the Guangzhou First People's Hospital, the Second Affiliated Hospital of South China University of Technology, Guangzhou 510641, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma with rapid progression towards metastasis has become the deadliest form of skin cancer. However, the mechanism of melanoma growth and metastasis is still unclear. Here, we found that miRNA-138 was lowly expressed and hypoxia-inducible factor 1α (HIF1α) was highly expressed in patients' melanoma tissue compared with the paracancerous tissues, and they had a significant negative correlation (r=-0.877,

Indexed as

HIF1αInvasionMelanomaMetastasismiRNA-138Proliferation

Identifiers

PMID31371307
PMCPMC6737980

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.