Evidence map›Paper›PMID 31371119›Full record

ArticleInternational journal of cardiology2020

In-hospital left ventricular thrombus following ST-elevation myocardial infarction.

Aiham Albaeni, Khaled Chatila, Hind A Beydoun, May A Beydoun, Mohammad Morsy, Wissam I Khalife

Abstract readMulticenter Study
In one paragraph

Article in International journal of cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
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  8. Review
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  14. In-Hospital acute ischemic stroke following ST-elevation myocardial infarction.International journal of cardiology. Heart & vasculature · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aiham AlbaeniDepartment of Medicine, University of Central Florida, Ocala, FL, United States of America. Electronic address: aialbaen@utmb.edu.
Khaled ChatilaDepartment of Medicine, Division of Cardiology, University of Texas Medical branch, Galveston, TX, United States of America.
Hind A BeydounDivision of Research Programs, Office of Education Training and Research, Fort Belvoir Community Hospital, Fort Belvoir, VA.
May A BeydounLaboratory of Epidemiology and Population Sciences, National Institute on Aging, NIA/NIH/IRP, Baltimore, MD, United States of America.
Mohammad MorsyDepartment of Medicine, Division of Cardiology, University of Texas Medical branch, Galveston, TX, United States of America.
Wissam I KhalifeDepartment of Medicine, Division of Cardiology, University of Texas Medical branch, Galveston, TX, United States of America.

Funding

Behavioral epidemiology of healthy agingZIAAG000199 · NIA · NATIONAL INSTITUTE ON AGING · PI ZONDERMAN, ALAN B · 2013 to 2019
$7.8M
Intramural NIH HHS ZIA AG000199
6 · The paper itself

Abstract

backgroundIn-hospital left ventricular (LV) thrombus following acute ST-elevation myocardial infarction (STEMI) has not been evaluated on a national scale and was the focus of this investigation.

methodsWe used the 2003 to 2013 Nationwide Inpatient Sample database to identify adults ≥18 years old with a principal diagnosis code of ST-elevation myocardial infarction. Patients were divided into two groups defined by the presence or absence of LV thrombus. Clinical characteristics and in-hospital outcomes were studied using relevant statistics. Multiple linear and logistic regression models were conducted to identify factors associated with LV thrombus.

resultsOf 1,035,888 STEMI patients hospitalized in the U. S from 2003 to 2013, 1982 (0.2%) developed acute in-hospital LV thrombus. Compared to no LV thrombus, patients with LV thrombus were more likely to have in-hospital complications; acute ischemic and hemorrhagic stroke, acute renal failure, gastrointestinal bleed, cardiogenic shock, in-hospital cardiac arrest and mortality. They also had longer mean length of stay and higher hospital charges. Factors associated with LV thrombus included: anterior/anterolateral STEMI, acute or chronic heart failure with reduced ejection fraction, atrial fibrillation, LV aneurysm, Left heart valvular disease, acute or chronic deep venous thrombosis/pulmonary embolism and alcohol abuse. Patients with LV thrombus were less likely to be female [AOR 0.66, 95% CI (0.51-0.84)].

conclusionThe identification of factors associated with early development of LV thrombus following STEMI, will help direct resources for specific high-risk group and prompt cost-effective therapies. Gender variability in LV thrombus development warrants further investigations.

Indexed as

AdolescentAdultAgedAged, 80 and overCost-Benefit AnalysisDatabases, FactualFemaleHospitalizationHospital MortalityHumansMaleMiddle AgedST Elevation Myocardial InfarctionThrombosisVentricular Dysfunction, LeftYoung AdultGender variationIn-hospital complicationsLeft ventricular thrombusResource utilizationST-elevation myocardial infarction

Identifiers

PMID31371119
PMCPMC6891157

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.