ArticleBMC plant biology2019
Genome-wide exploration and characterization of miR172/euAP2 genes in Brassica napus L. for likely role in flower organ development.
Article in BMC plant biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 41 citations in OpenAlex.
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- Genome-wide analysis of Phaseolus vulgaris L. miR172 gene family members under heavy metal stress.BMC genomics · 2026Article
- AnPlants (Basel, Switzerland) · 2025Article
- Genome-wide analysis of miR172-mediated response to heavy metal stress in chickpea (Cicer arietinum L.): physiological, biochemical, and molecular insights.BMC plant biology · 2024Article
- Genome-wide analysis of glutamate receptor gene family in allopolyploid Brassica napus and its diploid progenitors.Genetica · 2023Article
- Comparative transcriptomic analysis of male and females in the dioecious weeds Amaranthus palmeri and Amaranthus tuberculatus.BMC plant biology · 2023Article
- Article
- Identification of Conserved and Novel MicroRNAs with their Targets in Garden Pea (Bioinformatics and biology insights · 2023Article
- Multiple Functions of MiRNAs inLife (Basel, Switzerland) · 2022Review
- Identification and Analysis of the AP2 Subfamily Transcription Factors in the Pecan (International journal of molecular sciences · 2021Article
- Identification of miRNAs and their target genes in genic male sterility lines in Brassica napus by small RNA sequencing.BMC plant biology · 2021Article
- Circular RNAs Repertoire and Expression Profile duringInternational journal of molecular sciences · 2021Article
- Turnip mosaic virus in oilseed rape activates networks of sRNA-mediated interactions between viral and host genomes.Communications biology · 2020Article
- Molecular and Hormonal Regulation of Leaf Morphogenesis in Arabidopsis.International journal of molecular sciences · 2020Review
- Ectopic expression of miRNA172 in tomato (Solanum lycopersicum) reveals novel function in fruit development through regulation of an AP2 transcription factor.BMC plant biology · 2020Article
- Genome-Wide Identification and Analysis of the AP2 Transcription Factor Gene Family in Wheat (Frontiers in plant science · 2019Article
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11 authors at 1 institution in 1 country.
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Abstract
backgroundAPETALA2-like genes encode plant-specific transcription factors, some of which possess one microRNA172 (miR172) binding site. The miR172 and its target euAP2 genes are involved in the process of phase transformation and flower organ development in many plants. However, the roles of miR172 and its target AP2 genes remain largely unknown in Brassica napus (B. napus).
resultsIn this study, 19 euAP2 and four miR172 genes were identified in the B. napus genome. A sequence analysis suggested that 17 euAP2 genes were targeted by Bna-miR172 in the 3' coding region. EuAP2s were classified into five major groups in B.napus. This classification was consistent with the exon-intron structure and motif organization. An analysis of the nonsynonymous and synonymous substitution rates revealed that the euAP2 genes had gone through purifying selection. Whole genome duplication (WGD) or segmental duplication events played a major role in the expansion of the euAP2 gene family. A cis-regulatory element (CRE) analysis suggested that the euAP2s were involved in the response to light, hormones, stress, and developmental processes including circadian control, endosperm and meristem expression. Expression analysis of the miR172-targeted euAP2s in nine different tissues showed diverse spatiotemporal expression patterns. Most euAP2 genes were highly expressed in the floral organs, suggesting their specific functions in flower development. BnaAP2-1, BnaAP2-5 and BnaTOE1-2 had higher expression levels in late-flowering material than early-flowering material based on RNA-seq and qRT-PCR, indicating that they may act as floral suppressors.
conclusionsOverall, analyses of the evolution, structure, tissue specificity and expression of the euAP2 genes were peformed in B.napus. Based on the RNA-seq and experimental data, euAP2 may be involved in flower development. Three euAP2 genes (BnaAP2-1, BnaAP2-5 and BnaTOE1-2) might be regarded as floral suppressors. The results of this study provide insights for further functional characterization of the miR172 /euAP2 module in B.napus.
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