ArticleBMC medical imaging2019
The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans.
Article in BMC medical imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- Usefulness ofJournal of otology · 2026Article
- Odontogenic, atypical skull-base osteomyelitis: diagnostic pitfalls and therapeutic insights-a case report and mini-review.Frontiers in oral health · 2026Review
- Association between type of skull base osteomyelitis (SBO), source, and infection spread in patients with proven SBO.La Radiologia medica · 2025Article
- Skull Base Osteomyelitis and Parapharyngeal Abscess as Complications of Otitis Media in a Young Immunocompetent Man.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Central Skull Base Osteomyelitis in Queensland, Australia, 2010-2020.Open forum infectious diseases · 2024Article
- Imaging spectrum and complications of otogenic infections: insights into delayed diagnosis.The British journal of radiology · 2024Article
- Skull base infections, their complications, and management.The neuroradiology journal · 2024Review
- Exploring Skull Base Osteomyelitis: Comprehensive Case Reports and Management Strategies.Cureus · 2024Article
- Clinico-Radiological Evaluation for Longitudinal Assessment in Central Skull Base Osteomyelitis: Proposal of Novel Scoring System.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Atypical Skull-Base Osteomyelitis: Comprehensive Review and Multidisciplinary Management Viewpoints.Tropical medicine and infectious disease · 2023Review
- A 10-year review of malignant otitis externa: a new insight.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Multiple Cranial Neuropathies Due to a Mixed Infection in Skull Base Osteomyelitis: A Nanopore Sequencing Study.Journal of clinical neurology (Seoul, Korea) · 2021Article
- Skull base osteomyelitis: clinical and radiologic analysis of a rare and multifaceted pathological entity.Neurosurgical review · 2021Article
- Can imaging suggest the aetiology in skull base osteomyelitis? A systematic literature review.Polish journal of radiology · 2021Article
- Extracellular Vesicles: A Potential Biomarker for Quick Identification of Infectious Osteomyelitis.Frontiers in cellular and infection microbiology · 2020Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCentral skull-base osteomyelitis (CSBO) represents a life-threatening complication of external ear canal infection. Computed tomography (CT) and magnetic resonance imaging (MRI) play key roles in assessment of CSBO progression.
methodsTwelve patients with CSBO were included in a retrospective clinical study. In total, 62 scans (30 CTs and 32 MRIs) were performed to evaluate the extent of inflammatory changes. The scans were read independently by two radiologists specialised in imaging of the head and neck. The regions under the skull base were specified using the online Anatomy Atlas of the skull base. To clarify the timeline, the time period was divided into four parts, and inflammatory changes in the skull-base regions were tracked. Data were statistically analysed.
resultsIn early stages of the disease, CT scan detects inflammatory changes closely related to the stylomastoid foramen and medially to the posterior belly of the digastric muscle, changes which have been proved to be crucial for the diagnosis of CSBO. Later the infection spreads to the contralateral side causing demineralisation of the bones.
conclusionImaging methods play a crucial role not only in establishing the diagnosis, but also in anticipating the direction of infection spread underneath the skull base.
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