Evidence map›Paper›PMID 31370360›Full record

ArticleInternational journal of molecular sciences2019

Gadolinium Chloride Restores the Function of the Gap Junctional Intercellular Communication between Hepatocytes in a Liver Injury.

Le Yang, Chengbin Dong, Lei Tian, Xiaofang Ji, Lin Yang, Liying Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Rare Earths-The Answer to Everything.Molecules (Basel, Switzerland) · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Le YangDepartment of Cell Biology, Municipal Laboratory for Liver Protection and Regulation of Regeneration, Capital Medical University, Beijing 100069, China.
Chengbin DongDepartment of Cell Biology, Municipal Laboratory for Liver Protection and Regulation of Regeneration, Capital Medical University, Beijing 100069, China.
Lei TianDepartment of Cell Biology, Municipal Laboratory for Liver Protection and Regulation of Regeneration, Capital Medical University, Beijing 100069, China.
Xiaofang JiDepartment of Cell Biology, Municipal Laboratory for Liver Protection and Regulation of Regeneration, Capital Medical University, Beijing 100069, China.
Lin YangDepartment of Cell Biology, Municipal Laboratory for Liver Protection and Regulation of Regeneration, Capital Medical University, Beijing 100069, China.
Liying LiDepartment of Cell Biology, Municipal Laboratory for Liver Protection and Regulation of Regeneration, Capital Medical University, Beijing 100069, China. liliying@ccmu.edu.cn.
Capital Medical University · CN

Funding

Beijing Natural Science Foundation 7172019, 7164237National Natural and Science Foundation of China 81430013, 81670550, 81500465Project of Construction of Innovative Teams and Teacher Career Development for Universities and Colleges under Beijing Municipality IDHT20150502
6 · The paper itself

Abstract

backgroundGadolinium chloride (GdCl

methodsMice were administered GdCl

resultsCCl

conclusionGdCl3 administration protects functional GJIC between hepatocytes, and prevents the decrease of connexin proteins at mRNA and protein levels during liver injury, leading to the alleviation of chronic liver injury.

Indexed as

AnimalsAnti-Inflammatory AgentsBile DuctsCarbon TetrachlorideCell CommunicationChemical and Drug Induced Liver InjuryConnexin 26ConnexinsGadoliniumGap Junction beta-1 ProteinGap JunctionsGene Expression RegulationHepatocytesLigationLipopolysaccharidesLiverAnti-Inflammatory AgentsCarbon TetrachlorideConnexin 26ConnexinsGadoliniumgadolinium chlorideGap Junction beta-1 ProteinGjb2 protein, ratLipopolysaccharidesProtective Agentsconnexingadolinium chloridegap junctional intercellular communicationhepatocyteliver injury

Identifiers

PMID31370360
PMCPMC6695937
OpenAlexW2966111839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.